3-(Bromomethyl)pyridine hydrobromide (1:1)(CAS: 4916-55-6)

3-(Bromomethyl)pyridine hydrobromide (CAS: 4916-55-6) is a crystalline solid with a molecular weight of approximately 263.03 g/mol. It has a solubility of about 40 mg/mL in water and is soluble in common organic solvents like ethanol and acetone. It is moderately reactive with nucleophiles and has limited reactivity with electrophiles. The compound is stable under normal conditions but should be stored away from moisture to prevent hydrolysis.

3-(Bromomethyl)pyridine hydrobromide is typically synthesized by bromination of 3-methylpyridine followed by hydrobromination. The reaction involves the bromination of 3-methylpyridine using bromine in the presence of a base like sodium hydride. Hydrobromination is then performed using hydrogen bromide under anhydrous conditions to form the target compound. The yield is around 70-80%, and the process is carried out with a high level of selectivity.

3-(Bromomethyl)pyridine hydrobromide (CAS: 4916-55-6) is primarily used in the pharmaceutical industry for the synthesis of certain drug intermediates. It also has applications in the polymer industry for the production of functionalized polymers. Additionally, it can be used in the development of sensors and semiconductors due to its chemical properties, though its use in these sectors is less common.

When handling 3-(Bromomethyl)pyridine hydrobromide (CAS: 4916-55-6), it is important to wear appropriate personal protective equipment (PPE) such as gloves and safety goggles. The compound should be stored in a dry, cool, and well-ventilated area to prevent hydrolysis. Fume hoods should be used during preparation and handling to minimize exposure to fumes. In case of a spill, it should be cleaned up using appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.