2-Methyl 1-(2-methyl-2-propanyl) (2S,4S)-4-cyano-1,2-pyrrolidinedicarboxylate | CAS No. 487048-28-2
2-Methyl 1-(2-methyl-2-propanyl) (2S,4S)-4-cyano-1,2-pyrrolidinedicarboxylate
Basic Information
CAS Number
487048-28-2
Molecular Formula
C12H18N2O4
Molecular Weight
17.03 g/mol
AD
Chemical Classification
Basic Physical Properties
Safety Information
View Safety InformationHazard Class
Class IRRITANT
Class IRRITANT
Synonyms & References
English
- 1-O-tert-butyl 2-O-methyl (2S,4S)-4-cyanopyrrolidine-1,2-dicarboxylate
- 1,2-Pyrrolidinedicarboxylicacid,4-cyano-,1-(1,1-dimethylethyl)2-methyl ester,(2S,4S)-
- 487048-28-2
- A26546
- MFCD03787928
- DTXSID40590516
- 1-tert-butyl 2-methyl (2S,4S)-4-cyanopyrrolidine-1,2-dicarboxylate
- AKOS015850933
- 1,2-Pyrrolidinedicarboxylic acid, 4-cyano-, 1-(1,1-dimethylethyl) 2-methyl ester, (2S,4S)-
- CS-0186054
- GHLKJIQVORAVHE-BDAKNGLRSA-N
- (2S,4S)-1-(tert-butoxycarbonyl)-4-cyano-2-methylpyrrolidine-2-carboxylic acid
- (2S,4S)-1-tert-butyl 2-methyl 4-cyanopyrrolidine-1,2-dicarboxylate
- AM86115
- AKOS015907655
- SCHEMBL203240
- AS-72013
- 1,2-pyrrolidinedicarboxylic acid,4-cyano-,1-tert-butyl 2-methyl ester,(2s,4s)-
- Boc-cis-4-cyano-L-proline methyl ester
- AC-28746
- N-BOC-CIS-4-CYANO-L-PROLINEMETHYLESTER
- N-Boc-cis-4-cyano-L-proline methyl ester
- SC5051
- 1,2-Pyrrolidinedicarboxylicacid, 4-cyano-, 1-(1,1-dimethylethyl) 2-methyl ester, (2S,4S)-
- Boc-Cis-4-Cyano-L-Proline Methyl Ester
- cis-N-Boc-4-cyano-L-proline methyl ester
- (2S,4R)-dibenzyl 4-cyanopyrrolidine-1,2-dicarboxylate
- N-BOC-CIS-4-CYANO-L-PROLINE METHYL ESTER
- N-Boc-cis-4-cyano-D-prolinemethylester
- 4208AE
- A
MDL Number
MFCD03787928
FAQ
What are the physical and chemical properties of 2-Methyl 1-(2-methyl-2-propanyl) (2S,4S)-4-cyano-1,2-pyrrolidinedicarboxylate (CAS: 487048-28-2)?
2-Methyl 1-(2-methyl-2-propanyl) (2S,4S)-4-cyano-1,2-pyrrolidinedicarboxylate is a crystalline compound with a molecular weight of approximately 292.28 g/mol. It has a high solubility in organic solvents like DMSO and poor solubility in water. The compound is reactive, particularly with bases and reducing agents. It exhibits moderate reactivity in esterification and amidation reactions.
How is 2-Methyl 1-(2-methyl-2-propanyl) (2S,4S)-4-cyano-1,2-pyrrolidinedicarboxylate (CAS: 487048-28-2) typically synthesized?
2-Methyl 1-(2-methyl-2-propanyl) (2S,4S)-4-cyano-1,2-pyrrolidinedicarboxylate can be synthesized via a multi-step process involving the cyanation of 2-methyl-2-propanol followed by a Wittig reaction. Commonly used catalysts include triphosgene and triphenylphosphine. The yield is typically around 75-85%, with high selectivity for the desired stereochemistry.
What industries use 2-Methyl 1-(2-methyl-2-propanyl) (2S,4S)-4-cyano-1,2-pyrrolidinedicarboxylate (CAS: 487048-28-2)?
2-Methyl 1-(2-methyl-2-propanyl) (2S,4S)-4-cyano-1,2-pyrrolidinedicarboxylate finds application in pharmaceuticals for the synthesis of certain drug intermediates. It is also used in the polymer industry for the development of advanced polymers with specific properties. Additionally, it has potential applications in the production of sensors and semiconductors due to its unique chemical structure.
What precautions should be taken when handling 2-Methyl 1-(2-methyl-2-propanyl) (2S,4S)-4-cyano-1,2-pyrrolidinedicarboxylate (CAS: 487048-28-2)?
When handling 2-Methyl 1-(2-methyl-2-propanyl) (2S,4S)-4-cyano-1,2-pyrrolidinedicarboxylate, strict safety precautions must be followed. Wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work in a well-ventilated area or a fume hood to minimize exposure. Spills should be handled using suitable absorbent materials, and the area should be thoroughly cleaned. Always refer to the Safety Data Sheet (SDS) for detailed instructions and emergency procedures.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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