Amikacin B | CAS No. 48237-20-3

Amikacin B

Basic Information

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CAS Number

48237-20-3

Molecular Formula

C22H44N6O12

Molecular Weight

584.62 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Surfactants Anionic Surfactants

Polymers and Plastics Thermoplastics Polyolefins

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

SMILES

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C1C(C(C(C(C1NC(=O)C(CCN)O)OC2C(C(C(C(O2)CO)O)N)O)O)OC3C(C(C(C(O3)CN)O)O)N)N

InChI

InChI=1S/C22H44N6O12/c23-2-1-8(30)20(36)28-7-3-6(25)18(39-21-12(27)15(33)14(32)9(4-24)37-21)17(35)19(7)40-22-16(34)11(26)13(31)10(5-29)38-22/h6-19,21-22,29-35H,1-5,23-27H2,(H,28,36)/t6-,7-,8+,9?,10?,11+,12?,13-,14-,15-,16?,17?,18-,19?,21-,22-/m1/s1

InChIKey

YISFONZWEZUXDI-OUGKPOERSA-N

LogP

-4.11600

Complexity

820

Synonyms & References

English

Amikacin B
Amikacin B Sulfate
(2S)-4-amino-N-[(1R,4R,5R)-5-amino-4-[(2R,4R,5S)-3-amino-6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy-2-[(2S,4S,5S)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-hydroxycyclohexyl]-2-hydroxybut
BB-K26
(2S)-4-Amino-N-{(1R,4R,5R)-5-amino-2-[(3-amino-3-deoxy-alpha-D-threo-hexopyranosyl)oxy]-4-[(2,6-diamino-2,6-dideoxy-alpha-D-threo-hexopyranosyl)oxy]-3-hydroxycyclohexyl}-2-hydroxybutanamide
CID 71313139
DTXSID50746981
48237-20-3
(2S)-4-amino-N-[(1R,4R,5R)-5-amino-4-[(2R,4R,5S)-3-amino-6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy-2-[(2S,4S,5S)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-hydroxycyclohexyl]-2-hydroxybutanamide

FAQ

What is Amikacin B (CAS: 48237-20-3)?

Amikacin B (CAS: 48237-20-3) is a complex antibiotic with a distinctive amide structure. It is primarily used in the treatment of various bacterial infections due to its potent antibacterial properties. Amikacin B is a semi-synthetic derivative of kanamycin and is effective against a wide range of gram-negative bacteria.

What are the main uses of Amikacin B (CAS: 48237-20-3)?

Amikacin B (CAS: 48237-20-3) is mainly used in the treatment of infections caused by gram-negative bacteria, such as those affecting the respiratory and urinary tracts. It is also utilized in the prevention and treatment of infections in immunocompromised patients and in cases of multi-drug resistant bacteria.

Is Amikacin B (CAS: 48237-20-3) safe?

Amikacin B (CAS: 48237-20-3) is generally considered safe when used as directed. However, it can cause adverse effects such as kidney toxicity and hearing loss. Proper use under a healthcare provider's supervision and adherence to recommended dosages are crucial to ensure safety.

How should Amikacin B (CAS: 48237-20-3) be stored?

Amikacin B (CAS: 48237-20-3) should be stored in a cool, dry place away from direct sunlight and heat sources. It is recommended to keep it at a temperature not exceeding 25°C. The container should be a tightly sealed vial or bottle to prevent moisture and other contaminants from entering.