![N-[(3S)-1-(Dimethylcarbamoyl)-3-pyrrolidinyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide structure](https://static.chemtradehub.com/structs/101/1013920-15-4-a4c8.webp "N-[(3S)-1-(Dimethylcarbamoyl)-3-pyrrolidinyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide structure")
N-[(3S)-1-(Dimethylcarbamoyl)-3-pyrrolidinyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide
CAS Number:
1013920-15-4
Molecular Formula:
C23H26FN5O3
(3R)-3-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-3-(4-methylphenyl)propanoic acid | CAS No. 479064-98-7
(3R)-3-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-3-(4-methylphenyl)propanoic acid
Basic Information
CAS Number
479064-98-7
Molecular Formula
C25H23NO4
Molecular Weight
401.46 g/mol
AD
Basic Physical Properties
Synonyms & References
English
- CS-0153105
- PS-12471
- DTXSID70375893
- Fmoc-(R)-3-Amino-3-(4-methylphenyl)propionic acid
- AC-22053
- Fmoc-(R)-3-Amino-3-(4-methyl-phenyl)-propionic acid
- Fmoc-4-Methyl-D-b-phenylalanine
- (3R)-3-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(4-methylphenyl)propanoic acid
- Fmoc-D-3-amino-3-(4-methylphenyl)-propionic acid
- A50447
- (R)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(p-tolyl)propanoicacid
- AKOS015948729
- (3R)-3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(4-methylphenyl)propanoic acid
- Fmoc-(R)-3-Amino-3-(4-methylphenyl)-propionic acid
- MFCD03428011
- EN300-1163002
- Benzenepropanoic acid, b-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-4-methyl-,(bR)-
- 479064-98-7
- (R)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(p-tolyl)propanoic acid
- fmoc-(r)-3-amino-3-(4-methylphenyl)propanoic acid
- Benzenepropanoic acid, β-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-4-methyl-, (βR)-
- Fmoc-(R)-3-amino-3-(4-methylphenyl)propionic acid
- FMOC-(R)-3-AMINO-3-(4-METHYL-PHENYL)-PROPIONIC ACID
- Fmoc-ß-R-4-Methylphenylalanine
- Fmoc-(R)-3-Amino-3-(4-methyl-phenyl)propionic acid
MDL Number
MFCD03428011
FAQ
What are the physical and chemical properties of (3R)-3-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-3-(4-methylphenyl)propanoic acid (CAS: 479064-98-7)?
The (3R)-3-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-3-(4-methylphenyl)propanoic acid (CAS: 479064-98-7) is a crystalline compound with a molecular weight of approximately 464.45 g/mol. It has a low solubility in water but is soluble in organic solvents like methanol and chloroform. Chemically, it is reactive towards nucleophiles and can undergo esterification and amide formation. It is stable under normal conditions but should be stored in a cool, dry place away from direct sunlight.
How is (3R)-3-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-3-(4-methylphenyl)propanoic acid (CAS: 479064-98-7) typically synthesized?
(3R)-3-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-3-(4-methylphenyl)propanoic acid (CAS: 479064-98-7) is synthesized via a multi-step process involving protection of the carboxylic acid with fluorenylmethoxycarbonyl (Fmoc) group, followed by amide formation with the appropriate amine. Common solvents used include dichloromethane and triethylamine. The reaction typically yields 70-80% purity with high selectivity.
What industries use (3R)-3-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-3-(4-methylphenyl)propanoic acid (CAS: 479064-98-7)?
(3R)-3-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-3-(4-methylphenyl)propanoic acid (CAS: 479064-98-7) is primarily used in the pharmaceutical industry for the synthesis of complex natural products and drug precursors. It also finds applications in the polymer industry as a crosslinking agent and in the development of sensors and semiconductors.
What precautions should be taken when handling (3R)-3-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-3-(4-methylphenyl)propanoic acid (CAS: 479064-98-7)?
When handling (3R)-3-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-3-(4-methylphenyl)propanoic acid (CAS: 479064-98-7), ensure the use of appropriate personal protective equipment (PPE), including gloves, lab coat, and safety glasses. Work should be conducted in a well-ventilated area or fume hood. Spills should be handled with caution using appropriate absorbent materials and disposed of according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal information.
Related Compounds
![7-Methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid structure](https://static.chemtradehub.com/structs/101/1016505-59-1-4c54.webp "7-Methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid structure")
7-Methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid
CAS Number:
1016505-59-1
Molecular Formula:
C8H7N3O2
![2-Fluoro-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)benzoic acid structure](https://static.chemtradehub.com/structs/104/1048919-15-8-ba81.webp "2-Fluoro-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)benzoic acid structure")
2-Fluoro-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)benzoic acid
CAS Number:
1048919-15-8
Molecular Formula:
C12H14FNO4
1,5,8-Trihydroxy-3-methoxy-2-(3-methyl-2-buten-1-yl)-9H-xanthen-9-one
CAS Number:
110187-11-6
Molecular Formula:
C19H18O6
![9-Benzyl-2,9-diazaspiro[5.5]undecane dihydrochloride structure](https://static.chemtradehub.com/structs/119/1198286-24-6-4781.webp "9-Benzyl-2,9-diazaspiro[5.5]undecane dihydrochloride structure")
9-Benzyl-2,9-diazaspiro[5.5]undecane dihydrochloride
CAS Number:
1198286-24-6
Molecular Formula:
C16H26Cl2N2
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