Compound Q&A
How is (3R)-3-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-3-(4-methylphenyl)propanoic acid (CAS: 479064-98-7) typically synthesized?
Answer
![(3R)-3-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-3-(4-methylphenyl)propanoic acid](https://static.chemtradehub.com/structs/479/479064-98-7-feeb.webp "(3R)-3-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-3-(4-methylphenyl)propanoic acid")
(3R)-3-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-3-(4-methylphenyl)propanoic acid (CAS: 479064-98-7) is synthesized via a multi-step process involving protection of the carboxylic acid with fluorenylmethoxycarbonyl (Fmoc) group, followed by amide formation with the appropriate amine. Common solvents used include dichloromethane and triethylamine. The reaction typically yields 70-80% purity with high selectivity.
About
CAS No
479064-98-7
English Name
(3R)-3-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-3-(4-methylphenyl)propanoic acid
Molecular Formula
C25H23NO4
Molecular Weight
401.46 g/mol
SMILES
CC1=CC=C(C=C1)C(CC(=O)O)NC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24
InChIKey
QVNBKPSESKXKBL-HSZRJFAPSA-N
Last Updated: 2025-12-25 13:43
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