(3R)-3-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-3-(4-methylphenyl)propanoic acid(CAS: 479064-98-7)

The (3R)-3-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-3-(4-methylphenyl)propanoic acid (CAS: 479064-98-7) is a crystalline compound with a molecular weight of approximately 464.45 g/mol. It has a low solubility in water but is soluble in organic solvents like methanol and chloroform. Chemically, it is reactive towards nucleophiles and can undergo esterification and amide formation. It is stable under normal conditions but should be stored in a cool, dry place away from direct sunlight.

(3R)-3-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-3-(4-methylphenyl)propanoic acid (CAS: 479064-98-7) is synthesized via a multi-step process involving protection of the carboxylic acid with fluorenylmethoxycarbonyl (Fmoc) group, followed by amide formation with the appropriate amine. Common solvents used include dichloromethane and triethylamine. The reaction typically yields 70-80% purity with high selectivity.

(3R)-3-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-3-(4-methylphenyl)propanoic acid (CAS: 479064-98-7) is primarily used in the pharmaceutical industry for the synthesis of complex natural products and drug precursors. It also finds applications in the polymer industry as a crosslinking agent and in the development of sensors and semiconductors.

When handling (3R)-3-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-3-(4-methylphenyl)propanoic acid (CAS: 479064-98-7), ensure the use of appropriate personal protective equipment (PPE), including gloves, lab coat, and safety glasses. Work should be conducted in a well-ventilated area or fume hood. Spills should be handled with caution using appropriate absorbent materials and disposed of according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal information.