N-(4-Ethoxyphenyl)-3-hydroxy-2-naphthamide | CAS No. 4711-68-6

N-(4-Ethoxyphenyl)-3-hydroxy-2-naphthamide

Basic Information

CAS Number

4711-68-6

Molecular Formula

C19H17NO3

Molecular Weight

307.35 g/mol

AD

Basic Physical Properties

Melting Point

217~219℃

Boiling Point

438.7°C at 760 mmHg

Density

1.273

Flash Point

219.1 °C

Refractive Index

1.686

CCOC1=CC=C(C=C1)NC(=O)C2=CC3=CC=CC=C3C=C2O

InChI

InChI=1S/C19H17NO3/c1-2-23-16-9-7-15(8-10-16)20-19(22)17-11-13-5-3-4-6-14(13)12-18(17)21/h3-12,21H,2H2,1H3,(H,20,22)

InChIKey

FYJKEJZGNQVNLC-UHFFFAOYSA-N

LogP

4.196400000000003

Topological Polar Surface Area

58.56 Ų

Hydrogen Bond Donor/Acceptor

2 / 4

Complexity

392

Synonyms & References

English

  • EC 225-200-7
  • 2-Naphthalenecarboxamide, N-(4-ethoxyphenyl)-3-hydroxy-
  • AZOIC COUPLING COMPONENT 30
  • Q27210711
  • Cibanaphthol RPH
  • UNII-ED3VQI55T0
  • NSC 50690
  • 2-Naphtho-p-phenetidide, 3-hydroxy-
  • Naphthol AS-VL
  • CS-0362287
  • N-(4-ethoxyphenyl)-3-oxidanyl-naphthalene-2-carboxamide
  • AG-690/36740014
  • NS00007701
  • N-(4-ethoxyphenyl)-3-hydroxy-naphthalene-2-carboxamide
  • DTXSID5063570
  • NSC-50690
  • 2-HYDROXY-3-NAPHTHOYL-P-ETHOXYANILINE
  • cid_78443
  • BDBM80521
  • N-(4-ethoxyphenyl)-3-hydroxy-2-naphthamide
  • C.I. Azoic Coupling Component 30
  • HMS2886N22
  • EINECS 225-200-7
  • CHEBI:122078
  • AKOS000592774
  • NSC50690
  • MLS000736677
  • Azoic coupling component 46
  • NCGC00246827-01
  • SR-01000513141
  • C.I. 37559

MDL Number

MFCD00476996

Customs Code

2924299090

FAQ

What are the physical and chemical properties of N-(4-Ethoxyphenyl)-3-hydroxy-2-naphthamide (CAS: 4711-68-6)?

N-(4-Ethoxyphenyl)-3-hydroxy-2-naphthamide (CAS: 4711-68-6) is a crystalline solid with a molecular weight of approximately 280.29 g/mol. It has low water solubility and is soluble in organic solvents like ethanol and acetone. It is prone to hydrolysis and reacts with acids and bases. The compound is stable under normal storage conditions but should be protected from moisture and light.

How is N-(4-Ethoxyphenyl)-3-hydroxy-2-naphthamide (CAS: 4711-68-6) typically synthesized?

N-(4-Ethoxyphenyl)-3-hydroxy-2-naphthamide (CAS: 4711-68-6) is synthesized through a multi-step process involving the condensation of 4-ethoxyaniline with 2-naphthoic acid. The reaction is typically catalyzed by a Lewis acid such as zinc chloride, with good yield and selectivity. The product is then purified by recrystallization from an appropriate solvent.

What industries use N-(4-Ethoxyphenyl)-3-hydroxy-2-naphthamide (CAS: 4711-68-6)?

N-(4-Ethoxyphenyl)-3-hydroxy-2-naphthamide (CAS: 4711-68-6) is used in the pharmaceutical industry for the synthesis of certain antibiotics and antifungal agents. It also has applications in the polymer industry for modifying the properties of polymers and in the development of sensors and semiconductors.

What precautions should be taken when handling N-(4-Ethoxyphenyl)-3-hydroxy-2-naphthamide (CAS: 4711-68-6)?

When handling N-(4-Ethoxyphenyl)-3-hydroxy-2-naphthamide (CAS: 4711-68-6), it is important to wear personal protective equipment (PPE) including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or fume hood. Spills should be cleaned up immediately using an appropriate absorbent material. Consult the Safety Data Sheet (SDS) for detailed safety information and emergency procedures.

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