Compound Q&A

How is N-(4-Ethoxyphenyl)-3-hydroxy-2-naphthamide (CAS: 4711-68-6) typically synthesized?

Answer

N-(4-Ethoxyphenyl)-3-hydroxy-2-naphthamide
N-(4-Ethoxyphenyl)-3-hydroxy-2-naphthamide (CAS: 4711-68-6) is synthesized through a multi-step process involving the condensation of 4-ethoxyaniline with 2-naphthoic acid. The reaction is typically catalyzed by a Lewis acid such as zinc chloride, with good yield and selectivity. The product is then purified by recrystallization from an appropriate solvent.

About

CAS No 4711-68-6
English Name N-(4-Ethoxyphenyl)-3-hydroxy-2-naphthamide
Molecular Formula C19H17NO3
Molecular Weight 307.35 g/mol
SMILES CCOC1=CC=C(C=C1)NC(=O)C2=CC3=CC=CC=C3C=C2O
InChIKey FYJKEJZGNQVNLC-UHFFFAOYSA-N
Last Updated: 2026-03-05 02:11

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