2,4,6-Trimethylbenzenesulfonamide

Basic Information

View in Editor

CAS Number

4543-58-2

Molecular Formula

C9H13NO2S

Molecular Weight

199.27 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

SMILES

View in Editor

Cc1cc(C)c(c(C)c1)S(=O)(=O)N

InChI

InChI=1S/C9H13NO2S/c1-6-4-7(2)9(8(3)5-6)13(10,11)12/h4-5H,1-3H3,(H2,10,11,12)

InChIKey

YECJUZIGFPJWGQ-UHFFFAOYSA-N

LogP

1.25926

Topological Polar Surface Area

60.16 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Synonyms & References

English

2,4,6-Trimethylbenzenesulfonamide
2,4,6-Trimethylbenzenesulphonamide
2,4,6-trimethyl-benzenesulfonamide
2,4,6-trimethylbenzenesulfonylamide
2,4,6-trimethylphenylsulfonamide
2-Mesitylenesulfonamide
AC1Q6TOM
benzenesulfonamide, 2,4,6-trimethyl-
mesityl sulfonamide
mesitylenesulfonamide
mesitylenesulfonylamide
NSC87569
PubChem24038
SureCN113366
2,4,6-trimethylbenzene-1-sulfonamide

MDL Number

MFCD00463245

FAQ

What are the physical and chemical properties of 2,4,6-Trimethylbenzenesulfonamide (CAS: 4543-58-2)?

2,4,6-Trimethylbenzenesulfonamide (CAS: 4543-58-2) is a white crystalline solid with a molecular weight of approximately 218.25 g/mol. It has a low solubility in water but is more soluble in organic solvents like ethanol and acetone. Chemically, it is stable under normal conditions but can undergo sulfonation reactions. It is used in various applications due to its stability and reactivity.

How is 2,4,6-Trimethylbenzenesulfonamide (CAS: 4543-58-2) typically synthesized?

2,4,6-Trimethylbenzenesulfonamide is typically synthesized by reacting 2,4,6-trimethylbenzenesulfonyl chloride with ammonia in the presence of a suitable catalyst. The reaction is carried out under mild conditions, and the product can be isolated by crystallization. The yield is usually high, and the method is known for its good selectivity.

What industries use 2,4,6-Trimethylbenzenesulfonamide (CAS: 4543-58-2)?

2,4,6-Trimethylbenzenesulfonamide (CAS: 4543-58-2) is used in the pharmaceutical industry for the synthesis of certain medications. It is also utilized in the polymer industry as a sulfonamide derivative, enhancing the performance of polymers. Additionally, it finds applications in the semiconductor industry and as a reagent in analytical chemistry.

What precautions should be taken when handling 2,4,6-Trimethylbenzenesulfonamide (CAS: 4543-58-2)?

When handling 2,4,6-Trimethylbenzenesulfonamide (CAS: 4543-58-2), it is important to wear appropriate personal protective equipment (PPE), including gloves and safety goggles. Work should be conducted in a well-ventilated area or a fume hood to prevent inhalation. Spills should be cleaned up using appropriate absorbent materials, and the area should be well-ventilated before resuming work. Refer to the Safety Data Sheet (SDS) for more detailed information on handling and storage procedures.