1-(Chloromethyl)-2,4-difluorobenzene

Basic Information

View in Editor

CAS Number

452-07-3

Molecular Formula

C7H5ClF2

Molecular Weight

162.57 g/mol

Chemical Classification

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Melting Point

0°C

Boiling Point

60°C/10mmHg

Flash Point

62 ºC

Refractive Index

1.4910

SMILES

View in Editor

C1=CC(=C(C=C1F)F)CCl

InChI

InChI=1S/C7H5ClF2/c8-4-5-1-2-6(9)3-7(5)10/h1-3H,4H2

InChIKey

XPGHWBDZNQUUQD-UHFFFAOYSA-N

LogP

2.7036000000000007

Topological Polar Surface Area

0.0 Å²

Hydrogen Bond Donor/Acceptor

0 / 0

Complexity

108

Safety Information

View Safety Information

GHS Hazard Pictograms

H314

H318

Hazard Statement

H314 Causes severe skin burns and eye damage
Skin corrosion/irritation

H318 Causes serious eye damage
Serious eye damage/eye irritation

Hazard Class

Class 8 Class 8

Sensitiveness

Lachrymatory

Synonyms & References

English

PS-10668
D3493
FT-0609768
2,4-Difluorobenzyl chloride
XPGHWBDZNQUUQD-UHFFFAOYSA-N
452-07-3
J-507214
AM62158
MFCD01090988
1-(chloromethyl)-2,4-difluorobenzene
2,4-difluorobenzylchloride
EN300-61214
A22576
2,4-difluoro-benzyl chloride
DTXSID80371725
Benzene, 1-(chloromethyl)-2,4-difluoro-
alpha-Chloro-2,4-difluorotoluene
AC-9732
SY040263
AKOS000262025
CK1010
SCHEMBL1503215
FT-0656791
1-(Chloromethyl)-2,4-difluorobenzene
2,4-Difluorobenzyl Chloride
α-Chloro-2,4-difluorotoluene
2, 4-difluorobenzyl chloride
PubChem4912
1-(chloromethyl)-2,4-difluoro-benzene
KSC588M7L
STK503683

MDL Number

MFCD01090988

Customs Code

2903999090

FAQ

What regulatory guidelines apply to 1-(Chloromethyl)-2,4-difluorobenzene (CAS: 452-07-3)?

1-(Chloromethyl)-2,4-difluorobenzene (CAS: 452-07-3) is subject to various regulatory guidelines. It is classified under the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) as a toxic chemical. In the European Union, it is regulated by REACH (Registration, Evaluation, Authorization and Restriction of Chemicals) which may require notification of exposure and handling procedures. Additionally, the U.S. Environmental Protection Agency (EPA) and the Food and Drug Administration (FDA) have specific guidelines for the use and disposal of this compound, including risk assessment and management of hazardous waste involving this compound.

Are there alternatives to 1-(Chloromethyl)-2,4-difluorobenzene (CAS: 452-07-3) in synthesis?

There are several alternatives to 1-(Chloromethyl)-2,4-difluorobenzene (CAS: 452-07-3) in synthesis. Common substitutes include 1-(Bromomethyl)-2,4-difluorobenzene and 1-(Iodomethyl)-2,4-difluorobenzene. These compounds can serve similar functions in certain reactions. Other alternatives may include isomers or structurally similar compounds. The choice of alternative depends on the specific requirements of the synthesis and the desired chemical properties.

What is the market or research trend for 1-(Chloromethyl)-2,4-difluorobenzene (CAS: 452-07-3)?

The market for 1-(Chloromethyl)-2,4-difluorobenzene (CAS: 452-07-3) is currently stable, with growing interest in its use as a key intermediate in the production of pharmaceuticals and agrochemicals. Research trends indicate increasing focus on sustainable alternatives and green chemistry approaches. However, due to its toxic nature, there are ongoing efforts to develop less hazardous compounds. The demand for safer and more efficient synthetic routes is driving innovation in this area.

How should waste containing 1-(Chloromethyl)-2,4-difluorobenzene (CAS: 452-07-3) be handled?

Waste containing 1-(Chloromethyl)-2,4-difluorobenzene (CAS: 452-07-3) should be handled according to strict environmental and safety regulations. Waste liquid should be collected in appropriate containers and stored separately. Incineration is a common method for disposal, but it must be performed in an environmentally controlled incinerator to ensure complete combustion and minimize emissions. Professional waste disposal services are recommended to ensure compliance with local and international regulations. Proper precautions, including personal protective equipment (PPE), should be taken to protect personnel from exposure during handling and disposal processes.