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1-(Chloromethyl)-2,4-difluorobenzene(CAS: 452-07-3)

1-(Chloromethyl)-2,4-difluorobenzene
CAS Number

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Basic Information

Molecular Formula
C7H5ClF2
Molecular Weight
162.57 g/mol

Physical Properties

Melting Point
0°C
Boiling Point
60°C/10mmHg(lit.)
Flash Point
62 ºC

Chemical Identifiers

SMILES
C1=CC(=C(C=C1F)F)CCl
InChIKey
XPGHWBDZNQUUQD-UHFFFAOYSA-N

Database References

MDL Number
MFCD01090988

FAQ

1-(Chloromethyl)-2,4-difluorobenzene (CAS: 452-07-3) is subject to various regulatory guidelines. It is classified under the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) as a toxic chemical. In the European Union, it is regulated by REACH (Registration, Evaluation, Authorization and Restriction of Chemicals) which may require notification of exposure and handling procedures. Additionally, the U.S. Environmental Protection Agency (EPA) and the Food and Drug Administration (FDA) have specific guidelines for the use and disposal of this compound, including risk assessment and management of hazardous waste involving this compound.
There are several alternatives to 1-(Chloromethyl)-2,4-difluorobenzene (CAS: 452-07-3) in synthesis. Common substitutes include 1-(Bromomethyl)-2,4-difluorobenzene and 1-(Iodomethyl)-2,4-difluorobenzene. These compounds can serve similar functions in certain reactions. Other alternatives may include isomers or structurally similar compounds. The choice of alternative depends on the specific requirements of the synthesis and the desired chemical properties.
The market for 1-(Chloromethyl)-2,4-difluorobenzene (CAS: 452-07-3) is currently stable, with growing interest in its use as a key intermediate in the production of pharmaceuticals and agrochemicals. Research trends indicate increasing focus on sustainable alternatives and green chemistry approaches. However, due to its toxic nature, there are ongoing efforts to develop less hazardous compounds. The demand for safer and more efficient synthetic routes is driving innovation in this area.
Waste containing 1-(Chloromethyl)-2,4-difluorobenzene (CAS: 452-07-3) should be handled according to strict environmental and safety regulations. Waste liquid should be collected in appropriate containers and stored separately. Incineration is a common method for disposal, but it must be performed in an environmentally controlled incinerator to ensure complete combustion and minimize emissions. Professional waste disposal services are recommended to ensure compliance with local and international regulations. Proper precautions, including personal protective equipment (PPE), should be taken to protect personnel from exposure during handling and disposal processes.

Safety Notice

Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.

Always follow proper handling procedures

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