(Oxydi-2,1-phenylene)bis(dicyclohexylphosphine)

Basic Information

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CAS Number

434336-16-0

Molecular Formula

C36H52OP2

Molecular Weight

562.76 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Agricultural Chemicals Pesticides Insecticides

Basic Physical Properties

Melting Point

140-146 °C

Solubility

Insuluble (3.9E-8 g/L) (25 ºC),

SMILES

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C1(P(C2CCCCC2)C3CCCCC3)=CC=CC=C1OC4=CC=CC=C4P(C5CCCCC5)C6CCCCC6

InChI

InChI=1S/C36H52OP2/c1-5-17-29(18-6-1)38(30-19-7-2-8-20-30)35-27-15-13-25-33(35)37-34-26-14-16-28-36(34)39(31-21-9-3-10-22-31)32-23-11-4-12-24-32/h13-16,25-32H,1-12,17-24H2

InChIKey

HPFGZHCWLVSVKJ-UHFFFAOYSA-N

LogP

11.024099999999988

Topological Polar Surface Area

9.23 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Safety Information

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GHS Hazard Pictograms

H302

H312

H315

H319

H332

H335

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H312 Harmful in contact with skin
Acute toxicity, dermal

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H332 Harmful if inhaled
Acute toxicity, inhalation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

(Oxybis(2,1-phenylene))bis(dicyclohexylphosphine)
Bis(dicyclohexylphosphinophenyl) ether
Bis(2-dicyclohexylphosphinophenyl)ether
dicyclohexyl-[2-(2-dicyclohexylphosphanylphenoxy)phenyl]phosphane
(Oxydi-2,1-phenylene)bis[dicyclohexyl] phosphine

MDL Number

MFCD03058784

FAQ

What are the physical and chemical properties of (Oxydi-2,1-phenylene)bis(dicyclohexylphosphine) (CAS: 434336-16-0)?

The compound (Oxydi-2,1-phenylene)bis(dicyclohexylphosphine) is a white crystalline solid with a molecular weight of approximately 522.5 g/mol. It has low solubility in water but is soluble in organic solvents like chloroform and dichloromethane. Chemically, it is highly stable and non-reactive under normal conditions. It is used as a ligand in organophosphorus chemistry and coordination chemistry.

How is (Oxydi-2,1-phenylene)bis(dicyclohexylphosphine) (CAS: 434336-16-0) typically synthesized?

The compound is typically synthesized through the reaction of 2,1-phenylenebis(dihydroxy)dicyclohexylphosphine with dicyclohexylphosphine, using a suitable base like potassium carbonate. The process involves careful control of temperature and solvent to achieve high yield and selectivity. Common solvents used include N,N-dimethylformamide (DMF) or dimethyl sulfoxide (DMSO).

What industries use (Oxydi-2,1-phenylene)bis(dicyclohexylphosphine) (CAS: 434336-16-0)?

(Oxydi-2,1-phenylene)bis(dicyclohexylphosphine) is primarily used in the pharmaceutical industry as a ligand in transition metal catalysis, particularly in asymmetric synthesis. It is also used in the development of organophosphorus compounds and in polymer chemistry for its stabilizing properties.

What precautions should be taken when handling (Oxydi-2,1-phenylene)bis(dicyclohexylphosphine) (CAS: 434336-16-0)?

When handling (Oxydi-2,1-phenylene)bis(dicyclohexylphosphine), it is important to wear appropriate personal protective equipment (PPE), including gloves and safety goggles. The compound should be stored in a cool, dry place away from direct sunlight and flammable materials. In case of spill, it should be carefully cleaned up and disposed of according to the Material Safety Data Sheet (MSDS) guidelines.