(Oxydi-2,1-phenylene)bis(dicyclohexylphosphine)(CAS: 434336-16-0)

The compound (Oxydi-2,1-phenylene)bis(dicyclohexylphosphine) is a white crystalline solid with a molecular weight of approximately 522.5 g/mol. It has low solubility in water but is soluble in organic solvents like chloroform and dichloromethane. Chemically, it is highly stable and non-reactive under normal conditions. It is used as a ligand in organophosphorus chemistry and coordination chemistry.

The compound is typically synthesized through the reaction of 2,1-phenylenebis(dihydroxy)dicyclohexylphosphine with dicyclohexylphosphine, using a suitable base like potassium carbonate. The process involves careful control of temperature and solvent to achieve high yield and selectivity. Common solvents used include N,N-dimethylformamide (DMF) or dimethyl sulfoxide (DMSO).

(Oxydi-2,1-phenylene)bis(dicyclohexylphosphine) is primarily used in the pharmaceutical industry as a ligand in transition metal catalysis, particularly in asymmetric synthesis. It is also used in the development of organophosphorus compounds and in polymer chemistry for its stabilizing properties.

When handling (Oxydi-2,1-phenylene)bis(dicyclohexylphosphine), it is important to wear appropriate personal protective equipment (PPE), including gloves and safety goggles. The compound should be stored in a cool, dry place away from direct sunlight and flammable materials. In case of spill, it should be carefully cleaned up and disposed of according to the Material Safety Data Sheet (MSDS) guidelines.