6-(5-Chloropyridin-2-yl)-7-hydroxy-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-one

Basic Information

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CAS Number

43200-81-3

Molecular Formula

C11H7ClN4O2

Molecular Weight

262.65 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Physical State

Powder

Melting Point

240-242°C

SMILES

View in Editor

C1=CC(=NC=C1Cl)N2C(C3=NC=CN=C3C2=O)O

InChI

InChI=1S/C11H7ClN4O2/c12-6-1-2-7(15-5-6)16-10(17)8-9(11(16)18)14-4-3-13-8/h1-5,10,17H

InChIKey

FUUXOEKDNNWZTR-UHFFFAOYSA-N

LogP

1.1762999999999997

Topological Polar Surface Area

79.21000000000001 Å²

Hydrogen Bond Donor/Acceptor

1 / 6

Complexity

343

Safety Information

View Safety Information

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

6-(5-chloropyrid-2-yl)-5-hydroxy-7-oxo-5,6-dihydropyrrolo-[3,4-b]pyrazine
6-(5-Chloro-2-pyridyl)-6,7-dihydro-7-hydroxy-5H-pyrrolo[3,4-b]pyrazin-5-one
ZOPICLONE ALCOHOL
6-(5-chloropyrid-2-yl)-5-hydroxy-7-oxo-5,6-dihydropyrrolo[3,4-b]pyrazine
NS00057436
6-(5-Chloro-2-pyridyl)-7-hydroxy-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-one
RP-29307
GS-3250
RP-29753, (RS)-
6-(5-chloropyridin-2-yl)-7-hydroxy-7H-pyrrolo[3,4-b]pyrazin-5-one
(7rs)-6-(5-chloropyridin-2-yl)-7-hydroxy-6,7-dihydro-5h-pyrrolo[3,4-b]pyrazin-5-one
6-(5-chloropyrid-2-yl)-5-hydroxy-7-oxo-5,6-dihydro-pyrrolo-[3,4-b] pyrazine
6-(5-chloropyrid-2-yl)-5-hydroxy-7-oxo-5,6-dihydro-pyrrolo-[3,4-b]pyrazine
6-(5-chloropyrid-2-yl)-5-hydroxy-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazine
AKOS015856395
6-(5-chloranylpyridin-2-yl)-7-oxidanyl-7H-pyrrolo[3,4-b]pyrazin-5-one
6-(5-chloropyridin-2-yl)-7-hydroxy-5H,6H,7H-pyrrolo[3,4-b]pyrazin-5-one
(7RS)-6-(5-Chloropyridin-2-yl)-7-hydroxy-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-one; Zopiclone Imp. B (EP); Zopiclone Impurity B
DTXSID90866117
AC-260
5H-PYRROLO(3,4-B)PYRAZIN-5-ONE, 6-(5-CHLORO-2-PYRIDINYL)-6,7-DIHYDRO-7-HYDROXY-
A826216
ZOPICLONE IMPURITY B [EP IMPURITY]
43200-81-3
J-518036
MFCD02684321
6-(5-chloropyridin-2-yl)-5-hydroxy-7-oxo-5,6-dihydroprolo(3,4b)pyrazine
Zopiclone impurity B
6-(5-chloro-2-pyridinyl)-7-hydroxy-7H-pyrrolo[3,4-b]pyrazin-5-one
6-(5-chloro-2-pyridinyl]-6,7-dihydro-7-hydroxy-5H-pyrrolo[3,4-b]pyrazine-5-one
6-(5-chloro-pyridin-2-yl)-7-hydroxy-6,7-dihydro-pyrrolo[3,4-b]pyrazin-5-one

MDL Number

MFCD02684321

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 6-(5-Chloropyridin-2-yl)-7-hydroxy-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-one (CAS: 43200-81-3)?

6-(5-Chloropyridin-2-yl)-7-hydroxy-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-one is a crystalline solid with a molecular weight of approximately 294.03 g/mol. Its solubility in water is low, around 2 mg/L. It is relatively stable but can react with strong acids and bases. It has a pKa of around 5.5, indicating it can act as a weak acid.

How is 6-(5-Chloropyridin-2-yl)-7-hydroxy-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-one (CAS: 43200-81-3) typically synthesized?

6-(5-Chloropyridin-2-yl)-7-hydroxy-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-one is typically synthesized via a multistep process involving the reaction of 2-chloropyridine with 7-hydroxy-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-one. Suitable catalysts are used to enhance reactivity and selectivity, with overall yields of about 75%.

What industries use 6-(5-Chloropyridin-2-yl)-7-hydroxy-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-one (CAS: 43200-81-3)?

6-(5-Chloropyridin-2-yl)-7-hydroxy-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-one is used in the pharmaceutical industry for the development of anti-inflammatory and anti-allergic drugs. It also finds applications in the synthesis of other heterocyclic compounds for various chemical and biological studies.

What precautions should be taken when handling 6-(5-Chloropyridin-2-yl)-7-hydroxy-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-one (CAS: 43200-81-3)?

When handling 6-(5-Chloropyridin-2-yl)-7-hydroxy-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-one, it is essential to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or fume hood to minimize exposure. Spills should be handled using appropriate safety measures and materials as outlined in the safety data sheet (SDS).

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Compound Q&A

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Compound Q&A

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6-(5-Chloropyridin-2-yl)-7-hydroxy-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-one | CAS No. 43200-81-3

Basic Information

CAS Number

Molecular Formula

Molecular Weight

Chemical Classification

Basic Physical Properties

Physical State

Melting Point

Chemical Properties

SMILES

InChI

InChIKey

LogP

Topological Polar Surface Area

Hydrogen Bond Donor/Acceptor

Complexity

Safety Information

Hazard Statement

Synonyms & References

English

MDL Number

Customs Code

FAQ

What are the physical and chemical properties of 6-(5-Chloropyridin-2-yl)-7-hydroxy-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-one (CAS: 43200-81-3)?

How is 6-(5-Chloropyridin-2-yl)-7-hydroxy-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-one (CAS: 43200-81-3) typically synthesized?

What industries use 6-(5-Chloropyridin-2-yl)-7-hydroxy-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-one (CAS: 43200-81-3)?

What precautions should be taken when handling 6-(5-Chloropyridin-2-yl)-7-hydroxy-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-one (CAS: 43200-81-3)?

Related Compounds

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