(2R)-3-Butyn-2-ol

Basic Information

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CAS Number

42969-65-3

Molecular Formula

C4H6O

Molecular Weight

60.1 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Nitriles

Basic Physical Properties

Melting Point

-22.07°C (estimate)

Boiling Point

103°C

Refractive Index

n20/D 1.426(lit.)

Specific Rotation

46.7 º (neat)

SMILES

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CC(C#C)O

InChI

InChI=1S/C4H6O/c1-3-4(2)5/h1,4-5H,2H3/t4-/m1/s1

InChIKey

GKPOMITUDGXOSB-SCSAIBSYSA-N

LogP

0.3871

Topological Polar Surface Area

20.23 Å²

Hydrogen Bond Donor/Acceptor

1 / 1

Complexity

57.3

Safety Information

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Hazard Statement

H226 Flammable liquid and vapor
Flammable liquids

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Hazard Class

Class 6.1 Class 6.1

Synonyms & References

English

F17654
(+)-3-butyn-2-ol
3-Butyn-2-ol, (2R)-
BCP15480
AMY24232
42969-65-3
BB 0261027
AKOS005259799
PS-17837
(2R)-3-butyn-2-ol
DTXSID70274155
(R)-3-butyn-2-ol
(r)-(+)-alpha-methylpropargyl alcohol
(2R)-but-3-yn-2-ol
(R)-(+)-3-Butyn-2-ol
(R)-(-)-3-butyne-2-ol
(R)-but-3-yn-2-ol
A935293
(R)-(+)-3-Butyn-2-ol, 98%
CS-0094046
GKPOMITUDGXOSB-SCSAIBSYSA-N
B2909
A814381
EN300-84740
(R)-(+)-1-Butyn-3-ol
MFCD00211237
R-3-Butyn-2-ol
PubChem20211
DT1685
FCH1120206
OR16943

MDL Number

MFCD00211237

FAQ

What are the physical and chemical properties of (2R)-3-Butyn-2-ol (CAS: 42969-65-3)?

(2R)-3-Butyn-2-ol is a colorless liquid with a molecular weight of approximately 70.09 g/mol. It is slightly soluble in water but miscible with most organic solvents. This compound has a high reactivity due to its triple bond and alcohol functional group, making it prone to addition and substitution reactions.

How is (2R)-3-Butyn-2-ol (CAS: 42969-65-3) typically synthesized?

(2R)-3-Butyn-2-ol can be synthesized via hydrogenation of 3-butyne followed by hydroxylation. Alternatively, it can be prepared by the reduction of 2-bromobutane with sodium borohydride. The synthesis often involves the use of transition metal catalysts and requires careful control of reaction conditions to achieve high selectivity and yield.

What industries use (2R)-3-Butyn-2-ol (CAS: 42969-65-3)?

(2R)-3-Butyn-2-ol is used in the pharmaceutical industry for the synthesis of certain drugs, in the polymer industry as a monomer, and in the sensor industry for its reactivity in detection processes. Its use in semiconductor manufacturing is also reported, although on a smaller scale.

What precautions should be taken when handling (2R)-3-Butyn-2-ol (CAS: 42969-65-3)?

When handling (2R)-3-Butyn-2-ol, it is essential to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be contained and cleaned up using appropriate materials. Refer to the Safety Data Sheet (SDS) for detailed information on handling and disposal procedures.