2-Methyl-L-proline

Basic Information

View in Editor

CAS Number

42856-71-3

Molecular Formula

C6H11NO2

Molecular Weight

129.16 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

310°C

SMILES

View in Editor

CC1(CCCN1)C(=O)O

InChI

InChI=1S/C6H11NO2/c1-6(5(8)9)3-2-4-7-6/h7H,2-4H2,1H3,(H,8,9)/t6-/m0/s1

InChIKey

LWHHAVWYGIBIEU-LURJTMIESA-N

LogP

0.21310000000000007

Topological Polar Surface Area

49.33 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

135

Synonyms & References

English

63399-73-5
(S)-2-methyl-pyrrolidine-2-carboxylic acid
H-alpha-Me-Pro-OH
H--Me-Pro-OH
2-Methylproline
Calpha-methylproline
42856-71-3
AKOS016842490
2-methyl-L-proline
AC-23328
PD196071
H-(Me)Pro-OH
MFCD01318647
SCHEMBL697443
LWHHAVWYGIBIEU-LURJTMIESA-N
BCP18010
alpha-Methyl-L-proline, >=98.0% (TLC)
EN300-174676
Q27454210
HY-76962
CS-M1365
AB08716
L-Proline, 2-methyl-
S10668
AS-54490
16277-06-8
2-methyl-l-pro
(S)-2-Methyl-2-pyrrolidinecarboxylicacid
(S)-2-Methylproline
(S)-2-methylpyrrolidine-2-carboxylic acid
A6951

MDL Number

MFCD01318647

Customs Code

2933990090

FAQ

What regulatory guidelines apply to 2-Methyl-L-proline (CAS: 42856-71-3)?

2-Methyl-L-proline (CAS: 42856-71-3) falls under the classification of a chemical substance under the Globally Harmonized System of Classification and Labelling of Chemicals (GHS). It is regulated under the REACH (Registration, Evaluation, Authorisation and Restriction of Chemicals) in the EU and may be subject to FDA and EPA regulations in the USA. Manufacturers and importers must ensure compliance with these regulations for proper handling, labeling, and reporting.

Are there alternatives to 2-Methyl-L-proline (CAS: 42856-71-3) in synthesis?

While 2-Methyl-L-proline is a useful proline derivative, there are alternative proline analogs such as L-proline itself or other cyclic amino acids that can be used in synthesis. Other common alternatives include D-proline or substituted prolines, which may offer similar functionality with different reactivity profiles. The choice depends on the specific reaction conditions and desired properties of the final product.

What is the market or research trend for 2-Methyl-L-proline (CAS: 42856-71-3)?

The market for 2-Methyl-L-proline (CAS: 42856-71-3) is growing due to its applications in pharmaceuticals, peptides, and polymer synthesis. Recent research trends include its use in developing new peptide drugs and biodegradable polymers. The demand is also influenced by its reactivity and stability, making it a valuable reagent in organic synthesis. However, market fluctuations can be influenced by changes in regulatory requirements and availability.

How should waste containing 2-Methyl-L-proline (CAS: 42856-71-3) be handled?

Waste containing 2-Methyl-L-proline (CAS: 42856-71-3) should be collected in appropriate containers and stored under controlled conditions to prevent degradation or contamination. It should be disposed of through a professional waste disposal service that adheres to local and national regulations. Environmental protection measures, such as neutralizing the waste solution before disposal, should be taken to minimize ecological impact. Incineration is also a viable option for complete destruction of the waste material.