Methyl (3R)-3-pyrrolidinecarboxylate

Basic Information

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CAS Number

428518-43-8

Molecular Formula

C6H11NO2

Molecular Weight

129.16 g/mol

Basic Physical Properties

Boiling Point

170 ºC

Flash Point

57 ºC

SMILES

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COC(=O)C1CCNC1

InChI

InChI=1S/C6H11NO2/c1-9-6(8)5-2-3-7-4-5/h5,7H,2-4H2,1H3/t5-/m1/s1

InChIKey

VVWWZOKQKXPVIV-RXMQYKEDSA-N

LogP

-0.23110000000000003

Topological Polar Surface Area

38.33 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

114

Synonyms & References

English

SCHEMBL1161879
EN300-131835
(R)-methylpyrrolidine-3-carboxylate
428518-43-8
VVWWZOKQKXPVIV-RXMQYKEDSA-N
(R)-methyl pyrrolidine-3-carboxylate
methyl (R)-pyrrolidine-3-carboxylate
AKOS016843448
A26479
(R)-methyl-pyrrolidine-3-carboxylate
DTXSID30363771
3-PYRROLIDINECARBOXYLIC ACID, METHYL ESTER, (3R)-
methyl (3R)-pyrrolidine-3-carboxylate
(R)-Methyl pyrrolidine-3-carboxylate
3-Pyrrolidinecarboxylicacid, methyl ester, (3R)-
Ethyl (R)-3-Pyrrolidinecarboxylate
(R)-Pyrrolidine-3-carboxylic acid methyl ester

MDL Number

MFCD13191636

Customs Code

2933990090

FAQ

What regulatory guidelines apply to Methyl (3R)-3-pyrrolidinecarboxylate (CAS: 428518-43-8)?

Methyl (3R)-3-pyrrolidinecarboxylate (CAS: 428518-43-8) is subject to regulatory guidelines under the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) for hazardous chemicals. In the European Union, it must comply with the Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH) regulation. For use in food or pharmaceutical applications, FDA and EPA safety standards must also be adhered to. Detailed safety data sheets (SDS) should be available for handling and storage.

Are there alternatives to Methyl (3R)-3-pyrrolidinecarboxylate (CAS: 428518-43-8) in synthesis?

Several alternatives can be considered in the synthesis of Methyl (3R)-3-pyrrolidinecarboxylate (CAS: 428518-43-8). Commonly, racemic 3-pyrrolidinecarboxylic acid can be used as a starting material, followed by resolution. Other isomers such as the (3S)-isomer can also be used, though the (3R)-isomer may be more preferred for certain applications. Citric acid derivatives and cyclic amides are other possible alternatives depending on the specific requirements of the synthesis.

What is the market or research trend for Methyl (3R)-3-pyrrolidinecarboxylate (CAS: 428518-43-8)?

The market for Methyl (3R)-3-pyrrolidinecarboxylate (CAS: 428518-43-8) is growing due to its use in pharmaceuticals, agrochemicals, and fine chemicals. Research trends indicate increasing demand for chiral compounds, enhancing the interest in this specific isomer. Studies are also exploring its use as a chiral auxiliary in asymmetric synthesis, driving innovation in organic synthesis techniques.

How should waste containing Methyl (3R)-3-pyrrolidinecarboxylate (CAS: 428518-43-8) be handled?

Waste containing Methyl (3R)-3-pyrrolidinecarboxylate (CAS: 428518-43-8) should be collected in compatible containers and stored in a well-ventilated area. Incineration or professional waste disposal is recommended for safe disposal. Environmental protection precautions include ensuring no spillage and using appropriate personal protective equipment. It is crucial to follow local regulations and guidelines for hazardous waste management to prevent environmental contamination.