Compound Q&A

Are there alternatives to Methyl (3R)-3-pyrrolidinecarboxylate (CAS: 428518-43-8) in synthesis?

Answer

Methyl (3R)-3-pyrrolidinecarboxylate
Several alternatives can be considered in the synthesis of Methyl (3R)-3-pyrrolidinecarboxylate (CAS: 428518-43-8). Commonly, racemic 3-pyrrolidinecarboxylic acid can be used as a starting material, followed by resolution. Other isomers such as the (3S)-isomer can also be used, though the (3R)-isomer may be more preferred for certain applications. Citric acid derivatives and cyclic amides are other possible alternatives depending on the specific requirements of the synthesis.

About

English Name Methyl (3R)-3-pyrrolidinecarboxylate
Molecular Formula C6H11NO2
Molecular Weight 129.16 g/mol
SMILES COC(=O)C1CCNC1
InChIKey VVWWZOKQKXPVIV-RXMQYKEDSA-N
Last Updated: 2025-12-30 05:21

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