2,2-Difluoropropane-1,3-diol

Basic Information

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CAS Number

428-63-7

Molecular Formula

C3H6F2O2

Molecular Weight

112.08 g/mol

Chemical Classification

Fine Chemicals Specialty Chemicals UV Stabilizers

Electronic Chemicals Semiconductor Materials Etchants

Water Treatment Chemicals Disinfectants Chlorine Compounds

Basic Physical Properties

Boiling Point

250.9±35.0℃ at 760 mmHg

Density

1.334

Flash Point

105.5°C

Refractive Index

1.376

SMILES

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C(C(CO)(F)F)O

InChI

InChI=1S/C3H6F2O2/c4-3(5,1-6)2-7/h6-7H,1-2H2

InChIKey

AMCKYDINHDOOCB-UHFFFAOYSA-N

LogP

-0.3936999999999999

Topological Polar Surface Area

40.46 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

48.9

Synonyms & References

English

2,2-Difluoropropane-1,3-diol
2,2-DIFLUORO-1,3-PROPANEDIOL
1,3-Propanediol,2,2-difluoro
2,2-difluoro-1,3-bis-hydroxy-propane
2,2-Difluoro-3-hydroxy-propan-1-ol
2,2-difluoro-propane-1,3-diol
2,2-Difluor-propan-1,3-diol
1,3-Propanediol, 2,2-difluoro-
NSC32744
Fluorotelomer symmetric diols
AMCKYDINHDOOCB-UHFFFAOYSA-N
NOCAS_893584
STL555523
BBL101726
SY026989
2,2-difluoropropane-1,3-diol
CS-0094694
MFCD16619633
C3H6F2O2
NSC-32744
NSC 32744
PB42807
DB-181538
F8887-5540
F52367
AS-48669
A900814
DTXSID20195487
SCHEMBL711852
428-63-7
EN300-153017

MDL Number

MFCD16619633

Customs Code

2905590090

FAQ

What are the physical and chemical properties of 2,2-Difluoropropane-1,3-diol (CAS: 428-63-7)?

2,2-Difluoropropane-1,3-diol (CAS: 428-63-7) is a colorless, flammable liquid with a molecular weight of approximately 116.04 g/mol. It has a low solubility in water and is more soluble in organic solvents. This compound is moderately reactive, particularly with strong acids and bases. It is a crystalline solid at room temperature, with a melting point of 22-23°C and a boiling point of 86-87°C. It is used in chemical synthesis and as a reagent due to its reactivity and stability in specific conditions.

How is 2,2-Difluoropropane-1,3-diol (CAS: 428-63-7) typically synthesized?

2,2-Difluoropropane-1,3-diol (CAS: 428-63-7) is typically synthesized via the oxirane ring opening reaction of 2,2-difluoro-1,3-propanediol. Common methods involve the reaction of 2,2-difluoro-1,3-propanediol with water or other nucleophiles. The synthesis often uses sulfuric acid as a catalyst, providing a high yield of the desired product with good selectivity. The reaction conditions and catalysts can vary, but careful control is necessary to achieve the desired purity and yield.

What industries use 2,2-Difluoropropane-1,3-diol (CAS: 428-63-7)?

2,2-Difluoropropane-1,3-diol (CAS: 428-63-7) is used in various industries, particularly in the pharmaceutical sector for the synthesis of novel compounds, and in the polymer industry to enhance the properties of plastics. It also finds applications in the production of sensors and semiconductors due to its reactivity and chemical versatility. Its use in these industries highlights its importance in modern chemical manufacturing and research.

What precautions should be taken when handling 2,2-Difluoropropane-1,3-diol (CAS: 428-63-7)?

When handling 2,2-Difluoropropane-1,3-diol (CAS: 428-63-7), it is important to wear appropriate personal protective equipment (PPE) such as gloves and safety goggles. This compound is flammable, so avoid ignition sources and ensure good ventilation. Use a fume hood during handling to minimize inhalation risk. In case of a spill, use appropriate absorbent materials and follow the safety data sheet (SDS) guidelines for disposal. Always consult the SDS for detailed safety instructions and emergency procedures.