2,2-Difluoropropane-1,3-diol(CAS: 428-63-7)

2,2-Difluoropropane-1,3-diol (CAS: 428-63-7) is a colorless, flammable liquid with a molecular weight of approximately 116.04 g/mol. It has a low solubility in water and is more soluble in organic solvents. This compound is moderately reactive, particularly with strong acids and bases. It is a crystalline solid at room temperature, with a melting point of 22-23°C and a boiling point of 86-87°C. It is used in chemical synthesis and as a reagent due to its reactivity and stability in specific conditions.

2,2-Difluoropropane-1,3-diol (CAS: 428-63-7) is typically synthesized via the oxirane ring opening reaction of 2,2-difluoro-1,3-propanediol. Common methods involve the reaction of 2,2-difluoro-1,3-propanediol with water or other nucleophiles. The synthesis often uses sulfuric acid as a catalyst, providing a high yield of the desired product with good selectivity. The reaction conditions and catalysts can vary, but careful control is necessary to achieve the desired purity and yield.

2,2-Difluoropropane-1,3-diol (CAS: 428-63-7) is used in various industries, particularly in the pharmaceutical sector for the synthesis of novel compounds, and in the polymer industry to enhance the properties of plastics. It also finds applications in the production of sensors and semiconductors due to its reactivity and chemical versatility. Its use in these industries highlights its importance in modern chemical manufacturing and research.

When handling 2,2-Difluoropropane-1,3-diol (CAS: 428-63-7), it is important to wear appropriate personal protective equipment (PPE) such as gloves and safety goggles. This compound is flammable, so avoid ignition sources and ensure good ventilation. Use a fume hood during handling to minimize inhalation risk. In case of a spill, use appropriate absorbent materials and follow the safety data sheet (SDS) guidelines for disposal. Always consult the SDS for detailed safety instructions and emergency procedures.