N-(4-Aminobenzoyl)-L-glutamic acid

Basic Information

View in Editor

CAS Number

4271-30-1

Molecular Formula

C12H14N2O5

Molecular Weight

266.25 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

175 ºC (dec.)

Boiling Point

607.1℃ at 760 mmHg

Flash Point

321.0±31.5 °C

Refractive Index

1.6660 (estimate)

Vapor Pressure

0.0±1.8 mmHg at 25°C

Specific Rotation

-15 º (c=2% in 0.1N HCl)

SMILES

View in Editor

C1=CC(=CC=C1C(=O)NC(CCC(=O)O)C(=O)O)N

InChI

InChI=1S/C12H14N2O5/c13-8-3-1-7(2-4-8)11(17)14-9(12(18)19)5-6-10(15)16/h1-4,9H,5-6,13H2,(H,14,17)(H,15,16)(H,18,19)/t9-/m0/s1

InChIKey

GADGMZDHLQLZRI-VIFPVBQESA-N

LogP

0.3166000000000001

Topological Polar Surface Area

129.72 Å²

Hydrogen Bond Donor/Acceptor

5 / 7

Complexity

350

Safety Information

View Safety Information

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

Glutamic acid, N-(p-aminobenzoyl)-, L-
EINECS 224-261-7
HY-W011713
N-(p-Aminobenzoyl)glutamic acid
4-aminobenzoyl-l-glutamic acid
(4-Aminobenzoyl)-L-glutamic acid
BDBM50542900
(P-AMINOBENZOYL)-L-GLUTAMIC ACID
METHOTREXATE IMPURITY K [EP IMPURITY]
AKOS010366208
A-5000
CALCIUM FOLINATE IMPURITY A [EP IMPURITY]
L-Glutamic acid, N-(4-aminobenzoyl)-
4-Aminobenzoylglutamic acid
Q27130821
N-(4-aminobenzene-1-carbonyl)-L-glutamic acid
(2S)-2((4-AMINOBENZOYL)AMINO)PENTANEDIOIC ACID
DTXSID10873641
4-AMINOBENZOIC GLUTAMIC ACID
FOLIC ACID HYDRATE IMPURITY A [EP IMPURITY]
SCHEMBL63083
N-(4-Aminobenzoyl)-L-glutamic acid, >=98% (TLC)
N-(p-Aminobenzoyl)glutamic acid (VAN)
(S)-2-(4-Aminobenzamido)pentanedioic acid
p-Amino Benzamide Glutamic Acid
4271-30-1
9BKY99A8HJ
N-4-Aminobenzoyl-L-glutamic acid
N-(4-aminobenzoyl)-L-Glutamic acid (Folic Acid Imp A), Pharmaceutical Secondary Standard; Certified Reference Material
AKOS015855631
Folic acid Impurity A

MDL Number

MFCD00042821

Customs Code

2922421000

FAQ

What is N-(4-Aminobenzoyl)-L-glutamic acid (CAS: 4271-30-1)?

N-(4-Aminobenzoyl)-L-glutamic acid, with the CAS number 4271-30-1, is a synthetic compound commonly used in pharmaceutical research. It is a derivative of L-glutamic acid and contains an amino benzoyl group. This compound is known for its ability to act as a precursor in the synthesis of various drugs and is characterized by its acidic properties and potential for forming salts.

What are the main uses of N-(4-Aminobenzoyl)-L-glutamic acid (CAS: 4271-30-1)?

N-(4-Aminobenzoyl)-L-glutamic acid (CAS: 4271-30-1) is primarily used in pharmaceutical applications, particularly as an intermediate in the development of antibiotics and antiviral agents. It also finds use in research for drug discovery and in the production of certain specialty chemicals. Additionally, it may be employed in the formulation of nutritional supplements and as a component in biochemical assays.

Is N-(4-Aminobenzoyl)-L-glutamic acid (CAS: 4271-30-1) safe?

N-(4-Aminobenzoyl)-L-glutamic acid (CAS: 4271-30-1) is generally considered safe when handled properly. However, as with many chemical compounds, it should be used with caution. Protective measures such as gloves and safety goggles are recommended during handling. It is important to follow safety guidelines and regulations to ensure proper disposal and minimize exposure risks.

How should N-(4-Aminobenzoyl)-L-glutamic acid (CAS: 4271-30-1) be stored?

N-(4-Aminobenzoyl)-L-glutamic acid (CAS: 4271-30-1) should be stored in a cool, dry, and dark place to maintain its stability. It is best kept in a sealed container at a temperature below 25°C and away from moisture and direct sunlight. Proper storage helps prevent degradation and ensures the compound remains effective for its intended use.