4-bromo-7-chloro-1H-pyrrolo[2,3-c]pyridine

Basic Information

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CAS Number

425380-38-7

Molecular Formula

C7H4BrClN2

Molecular Weight

231.48 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

230-231°

SMILES

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C1=CNC2=C1C(=CN=C2Cl)Br

InChI

InChI=1S/C7H4BrClN2/c8-5-3-11-7(9)6-4(5)1-2-10-6/h1-3,10H

InChIKey

PIXLSAWNYQEIJG-UHFFFAOYSA-N

LogP

2.9788000000000006

Topological Polar Surface Area

28.68 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

155

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

4-Bromo-7-chloro-1H-pyrrolo[2,3-c]pyridine
1H-Pyrrolo[2,3-c]pyridine, 4-bromo-7-chloro-
4-BROMO-7-CHLORO-6-AZAINDOLE
bromochloropyrrolocpyridine
PIXLSAWNYQEIJG-UHFFFAOYSA-N
SBB097805
RW3753
RP13321
PB14984
FCH1406762
OR52671
4-bromo-7-chloropyrrolo[2,3-c]pyridine
AM803892
SY059000
AB0051921
AX8202208
Z4740
ST2
ST24028964
4-bromo-7-chloro-1H-pyrrolo[2,3-c]pyridine
SCHEMBL1763755
A849235
425380-38-7
EN300-1719809
4-Bromo-7-chloro-1H-pyrrolo[2 pound not3-c]pyridine
MFCD11848529
AKOS005073142
CS-W022115
KD-0240
DTXSID20452648
J-514788

MDL Number

MFCD11848529

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 4-bromo-7-chloro-1H-pyrrolo[2,3-c]pyridine (CAS: 425380-38-7)?

4-Bromo-7-chloro-1H-pyrrolo[2,3-c]pyridine is a crystalline solid with a molecular weight of approximately 253.03 g/mol. It is poorly soluble in water but soluble in organic solvents such as dichloromethane and acetonitrile. The compound is reactive towards nucleophiles, making it suitable for various chemical reactions. It has a melting point of around 135-137°C.

How is 4-bromo-7-chloro-1H-pyrrolo[2,3-c]pyridine (CAS: 425380-38-7) typically synthesized?

4-Bromo-7-chloro-1H-pyrrolo[2,3-c]pyridine can be synthesized via a multi-step reaction starting from 7-chloro-1H-pyrrolo[2,3-c]pyridine. The key steps involve bromination using N-bromosuccinimide (NBS) in the presence of a photoinitiator. This method provides good selectivity and yield, making it a common synthetic route.

What industries use 4-bromo-7-chloro-1H-pyrrolo[2,3-c]pyridine (CAS: 425380-38-7)?

4-Bromo-7-chloro-1H-pyrrolo[2,3-c]pyridine is primarily used in the pharmaceutical industry for the development of specific drug candidates. It is also utilized in the production of certain sensors and as a precursor in the synthesis of organic semiconductors. Its unique chemical functionality makes it valuable in these fields.

What precautions should be taken when handling 4-bromo-7-chloro-1H-pyrrolo[2,3-c]pyridine (CAS: 425380-38-7)?

When handling 4-bromo-7-chloro-1H-pyrrolo[2,3-c]pyridine, it is essential to use personal protective equipment (PPE) such as gloves, goggles, and lab coat. Work should be conducted in a well-ventilated area or fume hood. Spills should be cleaned up using absorbent materials and disposed of according to local regulations. Always consult the Material Safety Data Sheet (MSDS/SDS) for specific safety guidelines.