4-bromo-7-chloro-1H-pyrrolo[2,3-c]pyridine(CAS: 425380-38-7)

4-Bromo-7-chloro-1H-pyrrolo[2,3-c]pyridine is a crystalline solid with a molecular weight of approximately 253.03 g/mol. It is poorly soluble in water but soluble in organic solvents such as dichloromethane and acetonitrile. The compound is reactive towards nucleophiles, making it suitable for various chemical reactions. It has a melting point of around 135-137°C.

4-Bromo-7-chloro-1H-pyrrolo[2,3-c]pyridine can be synthesized via a multi-step reaction starting from 7-chloro-1H-pyrrolo[2,3-c]pyridine. The key steps involve bromination using N-bromosuccinimide (NBS) in the presence of a photoinitiator. This method provides good selectivity and yield, making it a common synthetic route.

4-Bromo-7-chloro-1H-pyrrolo[2,3-c]pyridine is primarily used in the pharmaceutical industry for the development of specific drug candidates. It is also utilized in the production of certain sensors and as a precursor in the synthesis of organic semiconductors. Its unique chemical functionality makes it valuable in these fields.

When handling 4-bromo-7-chloro-1H-pyrrolo[2,3-c]pyridine, it is essential to use personal protective equipment (PPE) such as gloves, goggles, and lab coat. Work should be conducted in a well-ventilated area or fume hood. Spills should be cleaned up using absorbent materials and disposed of according to local regulations. Always consult the Material Safety Data Sheet (MSDS/SDS) for specific safety guidelines.