1,1,2,2-Tetrafluoro-1-methoxyethane

Basic Information

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CAS Number

425-88-7

Molecular Formula

C3H4F4O

Molecular Weight

132.06 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Specialty Chemicals UV Stabilizers

Electronic Chemicals Semiconductor Materials Etchants

Water Treatment Chemicals Disinfectants Chlorine Compounds

Basic Physical Properties

Melting Point

-107°C

Boiling Point

36.5 ºC

Flash Point

-20 ºC

Refractive Index

1.284

SMILES

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COC(C(F)F)(F)F

InChI

InChI=1S/C3H4F4O/c1-8-3(6,7)2(4)5/h2H,1H3

InChIKey

YQQHEHMVPLLOKE-UHFFFAOYSA-N

LogP

1.4907000000000001

Topological Polar Surface Area

9.23 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

71.7

Safety Information

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Hazard Statement

H225 Highly Flammable liquid and vapor
Flammable liquids

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Hazard Class

Class 3 Class 3

Synonyms & References

English

AKOS005063434
MFCD00042106
J-522646
M2514
1,1,2,2-Tetrafluoroethyl methyl ether
SCHEMBL29222
1,1,2,2-tetrafluoro-1-methoxy-ethane
Methyl1,1,2,2-tetrafluoroethylether
DTXSID40195282
YQQHEHMVPLLOKE-UHFFFAOYSA-N
Methyl 2H-Tetrafluoroethyl Ether
HFE-254
425-88-7
Ethane, 1,1,2,2-tetrafluoro-1-methoxy-
C79ZK3BQ7M
InChI=1/C3H4F4O/c1-8-3(6,7)2(4)5/h2H,1H3
YQQHEHMVPLLOKE-UHFFFAOYSA-
AS-31036
1,1,2,2-Tetrafluoro-1-methoxyethane
EINECS 207-039-4
1-Methoxy-1,1,2,2-tetrafluoroethane
FT-0605968
Methyl 1,1,2,2-tetrafluoroethyl ether
NS00019084
methyl 1,1,2,2-tetrafluoroethyl ether
1,1,2,2-tetrafluoro-1-methoxyethane
1,1,2,2-Tetrafluoroethylmethylether
C3H4F4O
PC6784
FCH917371
5001AJ

MDL Number

MFCD00042106

Customs Code

2909199090

FAQ

What are the physical and chemical properties of 1,1,2,2-Tetrafluoro-1-methoxyethane (CAS: 425-88-7)?

1,1,2,2-Tetrafluoro-1-methoxyethane is a colorless, clear, and volatile liquid with a low boiling point of 26.9°C. Its molecular weight is approximately 146.03 g/mol. It has low solubility in water but is miscible with most organic solvents. It is not highly reactive under normal conditions, but it can be slightly flammable and must be handled with care. It does not form explosive mixtures with air. The compound is used in various applications due to its unique physicochemical properties.

How is 1,1,2,2-Tetrafluoro-1-methoxyethane (CAS: 425-88-7) typically synthesized?

1,1,2,2-Tetrafluoro-1-methoxyethane is typically synthesized through a fluoroalkylation reaction involving 2-chloro-1,1,2,2-tetrafluoroethane and methanol in the presence of an organocatalyst. The reaction is carried out under mild conditions to achieve high selectivity and yield. The process involves the substitution of the chlorine atom with a methoxy group, generating the desired product.

What industries use 1,1,2,2-Tetrafluoro-1-methoxyethane (CAS: 425-88-7)?

1,1,2,2-Tetrafluoro-1-methoxyethane is used in various industries including pharmaceuticals, as a solvent in the production of APIs and excipients; in polymers, as a monomer for producing fluoropolymers; in sensors, as a detector gas; and in semiconductors, as a cleaning agent due to its low surface tension and good dielectric properties.

What precautions should be taken when handling 1,1,2,2-Tetrafluoro-1-methoxyethane (CAS: 425-88-7)?

When handling 1,1,2,2-Tetrafluoro-1-methoxyethane, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. It should be stored in a cool, dry place, away from sources of ignition and incompatible materials. Fume hoods should be used when working with the compound to avoid inhalation. Spills should be handled by using appropriate spill kits and in accordance with Material Safety Data Sheets (MSDS/SDS). Always follow local safety regulations and guidelines for handling flammable and reactive chemicals.