Compound Q&A

How is 1,1,2,2-Tetrafluoro-1-methoxyethane (CAS: 425-88-7) typically synthesized?

Answer

1,1,2,2-Tetrafluoro-1-methoxyethane
1,1,2,2-Tetrafluoro-1-methoxyethane is typically synthesized through a fluoroalkylation reaction involving 2-chloro-1,1,2,2-tetrafluoroethane and methanol in the presence of an organocatalyst. The reaction is carried out under mild conditions to achieve high selectivity and yield. The process involves the substitution of the chlorine atom with a methoxy group, generating the desired product.

About

CAS No 425-88-7
English Name 1,1,2,2-Tetrafluoro-1-methoxyethane
Molecular Formula C3H4F4O
Molecular Weight 132.06 g/mol
SMILES COC(C(F)F)(F)F
InChIKey YQQHEHMVPLLOKE-UHFFFAOYSA-N
Last Updated: 2025-09-29 09:43

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