2-Aminoisonicotinonitrile

Basic Information

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CAS Number

42182-27-4

Molecular Formula

C6H5N3

Molecular Weight

119.12 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Nitriles

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

146-152°C

Boiling Point

297.7℃ at 760 mmHg

Density

1.2300

Water Solubility

Slightly soluble in water.

Flash Point

133.8℃

SMILES

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C1=CN=C(C=C1C#N)N

InChI

InChI=1S/C6H5N3/c7-4-5-1-2-9-6(8)3-5/h1-3H,(H2,8,9)

InChIKey

GEEAYLFEIFJFGP-UHFFFAOYSA-N

LogP

1.11668

Complexity

135

Safety Information

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Hazard Statement

H301 Toxic if swallowed
Acute toxicity, oral

H317 May cause an allergic skin reaction
Sensitization, Skin

Hazard Class

Class 6.1 Class 6.1

Synonyms & References

English

BCP22870
2-aminoisonicotinonitrile
DTXSID40426745
SCHEMBL312451
2-Amino-4-cyanopyridine, AldrichCPR
CS-D1178
2-Amino-4-Cyano Pyridine
AKOS000168276
2-Amino-4-cyanopyridine
BCP9000088
EN300-50615
SY005912
2-Amino-isonicotinonitrile
PS-5786
GEO-03415
42182-27-4
4-cyanopyridin-2-amine
2-amino-4-cyano-pyridine
Flucloxacillin Penilloic Acid
MFCD03791310
2-Amino-4-cyanopyridin
GEEAYLFEIFJFGP-UHFFFAOYSA-N
2-aminopyridine-4-carbonitrile
PB17329
Z295203360
AM20070060
FT-0601263
4-cyano-2-aminopyridine
2-Aminoisonicotinonitrile
4-Cyano-2-pyridinamine
Isonicotinonitrile,2-amino- (7CI)

MDL Number

MFCD03791310

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 2-Aminoisonicotinonitrile (CAS: 42182-27-4)?

2-Aminoisonicotinonitrile is a crystalline solid with a molecular weight of approximately 147.11 g/mol. It has a low solubility in water but is more soluble in organic solvents. Chemically, it is moderately reactive and can act as both an amine and a nitrile group. It is typically prepared by amidation and nitrile formation from other precursors.

How is 2-Aminoisonicotinonitrile (CAS: 42182-27-4) typically synthesized?

2-Aminoisonicotinonitrile is usually synthesized through amidation of isonicotinoyl chloride with ammonia or an amine. The reaction is typically catalyzed by an acid or base, and yields are generally good. The process involves the formation of an amide bond followed by the introduction of a nitrile group.

What industries use 2-Aminoisonicotinonitrile (CAS: 42182-27-4)?

2-Aminoisonicotinonitrile finds applications in pharmaceuticals, where it is used as a precursor for drug synthesis. It is also utilized in the production of dyes and pigments in the chemical industry. Additionally, it is employed in polymer synthesis and as a reagent in analytical chemistry for sensor development.

What precautions should be taken when handling 2-Aminoisonicotinonitrile (CAS: 42182-27-4)?

When handling 2-Aminoisonicotinonitrile, proper personal protective equipment (PPE) is essential, including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to avoid inhalation of vapors. Spills should be handled carefully using appropriate tools and materials. Always consult the Safety Data Sheet (SDS) for specific guidelines on handling and disposal.