Trifluoromethanesulfonyl chloride

Basic Information

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CAS Number

421-83-0

Molecular Formula

CClF3O2S

Molecular Weight

168.52 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Fine Chemicals Specialty Chemicals UV Stabilizers

Electronic Chemicals Semiconductor Materials Etchants

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Water Treatment Chemicals Disinfectants Chlorine Compounds

Basic Physical Properties

Boiling Point

31°C

Water Solubility

Hydrolyzes with water.

Flash Point

32°C

Refractive Index

n20/D 1.334(lit.)

Vapor Pressure

10.36 psi ( 20 °C)

SMILES

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C(F)(F)(F)S(=O)(=O)Cl

InChI

InChI=1S/CClF3O2S/c2-8(6,7)1(3,4)5

InChIKey

GRGCWBWNLSTIEN-UHFFFAOYSA-N

LogP

1.0748000000000002

Topological Polar Surface Area

34.14 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

161

Safety Information

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Hazard Statement

H290 May be corrosive to metals
Corrosive to Metals

H314 Causes severe skin burns and eye damage
Skin corrosion/irritation

Hazard Class

Class 8 Class 8

Sensitiveness

Lachrymatory

Synonyms & References

English

trifluoromethanesufonyl chloride
SCHEMBL21681
trifluoromethylsulphonyl chloride
CF3SO2Cl
CS-B0875
EINECS 207-009-0
421-83-0
CClF3O2S
MFCD00007451
AKOS005063740
Trifluoromethanesulfonyl chloride, >=99%
T1027
Trifluoromethane sulphonyl chloride
trifluoromethanesulphonic acid chloride
Triflyl chloride
BP-10786
FT-0676320
triflic chloride
trifluoromethyl sulphonyl chloride
trifluoromethane sulfonylchloride
1,1,1-trifluoromethanesulfonyl chloride
FS-4166
Methanesulfonyl chloride, trifluoro-
tris(fluoranyl)methanesulfonyl chloride
NS00042815
A825799
Trifluoromethanesulphonyl chloride
TRIFLUOROMETHYLSULFONYL CHLORIDE
DTXSID50194943
Trifluoromathanesulfonyl chloride
D92440

MDL Number

MFCD00007451

Customs Code

2904909090

FAQ

What regulatory guidelines apply to trifluoromethanesulfonyl chloride (CAS: 421-83-0)?

Trifluoromethanesulfonyl chloride (CAS: 421-83-0) is regulated under the Globally Harmonized System of Classification and Labelling of Chemicals (GHS), REACH in the European Union, and FDA regulations for use in pharmaceuticals. It is classified as a skin and eye irritant and a carcinogen. Companies must comply with specific handling, storage, and disposal requirements under these regulations.

Are there alternatives to trifluoromethanesulfonyl chloride (CAS: 421-83-0) in synthesis?

Trifluoromethanesulfonyl chloride is a potent reagent, but alternatives include trifluoromethyl triflate and triflic anhydride. These offer similar functionality but with different reactivity profiles. In some cases, more environmentally friendly alternatives like perfluoromethyl chlorosulfonate may be used.

What is the market or research trend for trifluoromethanesulfonyl chloride (CAS: 421-83-0)?

There is increasing interest in trifluoromethanesulfonyl chloride due to its use in pharmaceutical and organic synthesis. The market trend shows steady growth driven by its applications in the development of new drugs and materials. Research is focusing on its use in less toxic alternatives for safer chemical processes.

How should waste containing trifluoromethanesulfonyl chloride (CAS: 421-83-0) be handled?

Waste containing trifluoromethanesulfonyl chloride should be collected in a sealed, labeled container and stored under adequate ventilation. It should be disposed of through a regulated hazardous waste collection service. Environmental precautions include ensuring no release to the air or water. Proper incineration or professional disposal services are recommended to avoid environmental contamination.