Trifluoromethanesulfonyl chloride(CAS: 421-83-0)

CAS Number
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Other Suppliers for Trifluoromethanesulfonyl chloride
Basic Information
Molecular Formula
CClF3O2S
Molecular Weight
168.52 g/mol
Physical Properties
Boiling Point
31°C
Flash Point
32°C
Water Solubility
Hydrolyzes with water.
Chemical Identifiers
SMILES
C(F)(F)(F)S(=O)(=O)Cl
InChIKey
GRGCWBWNLSTIEN-UHFFFAOYSA-N
Database References
MDL Number
MFCD00007451
Beilstein Registry Number
1812016
FAQ
Trifluoromethanesulfonyl chloride (CAS: 421-83-0) is regulated under the Globally Harmonized System of Classification and Labelling of Chemicals (GHS), REACH in the European Union, and FDA regulations for use in pharmaceuticals. It is classified as a skin and eye irritant and a carcinogen. Companies must comply with specific handling, storage, and disposal requirements under these regulations.
Trifluoromethanesulfonyl chloride is a potent reagent, but alternatives include trifluoromethyl triflate and triflic anhydride. These offer similar functionality but with different reactivity profiles. In some cases, more environmentally friendly alternatives like perfluoromethyl chlorosulfonate may be used.
There is increasing interest in trifluoromethanesulfonyl chloride due to its use in pharmaceutical and organic synthesis. The market trend shows steady growth driven by its applications in the development of new drugs and materials. Research is focusing on its use in less toxic alternatives for safer chemical processes.
Waste containing trifluoromethanesulfonyl chloride should be collected in a sealed, labeled container and stored under adequate ventilation. It should be disposed of through a regulated hazardous waste collection service. Environmental precautions include ensuring no release to the air or water. Proper incineration or professional disposal services are recommended to avoid environmental contamination.
Safety Notice
Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.
Always follow proper handling procedures

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