Compound Q&A
Are there alternatives to trifluoromethanesulfonyl chloride (CAS: 421-83-0) in synthesis?
Answer
Trifluoromethanesulfonyl chloride is a potent reagent, but alternatives include trifluoromethyl triflate and triflic anhydride. These offer similar functionality but with different reactivity profiles. In some cases, more environmentally friendly alternatives like perfluoromethyl chlorosulfonate may be used.
About
CAS No
421-83-0
English Name
Trifluoromethanesulfonyl chloride
Molecular Formula
CClF3O2S
Molecular Weight
168.52 g/mol
SMILES
C(F)(F)(F)S(=O)(=O)Cl
InChIKey
GRGCWBWNLSTIEN-UHFFFAOYSA-N
Last Updated: 2025-09-08 18:31
