Fenofibrate EP Impurity B (Fenofibrate USP Related Compound B, Fenofibric Acid)

Basic Information

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CAS Number

42017-89-0

Molecular Formula

C17H15ClO4

Molecular Weight

318.76 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Physical State

Powder

Melting Point

179.0 to 183.0 deg-C

Boiling Point

486.5°C at 760 mmHg

Density

1.3±0.1 g/cm3

Flash Point

248.0±25.9 °C

SMILES

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CC(C)(C(=O)O)OC1=CC=C(C=C1)C(=O)C2=CC=C(C=C2)Cl

InChI

InChI=1S/C17H15ClO4/c1-17(2,16(20)21)22-14-9-5-12(6-10-14)15(19)11-3-7-13(18)8-4-11/h3-10H,1-2H3,(H,20,21)

InChIKey

MQOBSOSZFYZQOK-UHFFFAOYSA-N

LogP

3.8130000000000033

Topological Polar Surface Area

63.60000000000001 Å²

Hydrogen Bond Donor/Acceptor

1 / 4

Complexity

405

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H410 Very toxic to aquatic life with long lasting effects
Hazardous to the aquatic environment, long-term hazard

Hazard Class

Class 9 Class 9

Synonyms & References

English

Fenofibricacid
NS00000286
MFCD00792461
AC-22277
Fenofibric acid (Standard)
BDBM28700
D11579
CCRIS 7302
A825720
LF 153
DTXSID8041030
FENOFIBRIC ACID
ABT 335
Fenofibrate impurity B, European Pharmacopoeia (EP) Reference Standard
SY052754
CHEMBL981
FENOFIBRIC ACID DELAYED-RELEASE
FNF Acid
FENOFIBRIC ACID (USP-RS)
2-[4-(4-Chlorobenzoyl)phenoxy]-2-methylpropanoic Acid (Fenofibric Acid)
Q27077290
CCG-213311
CHEBI:83469
KS-1234
AMY25229
Fibricor
D83849
2-[4-(4-Chloro-benzoyl)-phenoxy]-2-methyl-propionic acid
Fenofibric acid
FENOFIBRIC ACID [USP-RS]
HY-B0760

MDL Number

MFCD00792461

FAQ

What is Fenofibrate EP Impurity B (CAS: 42017-89-0)?

Fenofibrate EP Impurity B, also known as Fenofibric Acid, is a chemical compound with the CAS number 42017-89-0. It is a derivative of fibric acid and is commonly used as an impurity in the production of fenofibrate, a drug used to treat hyperlipidemia. The compound is a white to pale yellow solid with a molecular formula of C14H18O4 and exhibits solubility in polar solvents.

What are the main uses of Fenofibrate EP Impurity B (CAS: 42017-89-0)?

Fenofibrate EP Impurity B (Fenofibric Acid) is primarily used in the pharmaceutical industry as an impurity in fenofibrate synthesis. It may also be used in quality control processes to ensure the purity of fenofibrate drugs. Additionally, it serves as a research compound for studying metabolic pathways and drug interactions related to fibric acid derivatives.

Is Fenofibrate EP Impurity B (CAS: 42017-89-0) safe?

Fenofibrate EP Impurity B (Fenofibric Acid) is generally considered safe when handled properly, though it may have potential toxicity if ingested or inhaled in large amounts. Safety standards recommend that it be treated with caution, using appropriate personal protective equipment (PPE). It is important to follow guidelines for chemical handling to minimize risks in laboratory and industrial settings.

How should Fenofibrate EP Impurity B (CAS: 42017-89-0) be stored?

Fenofibrate EP Impurity B (CAS: 42017-89-0) should be stored in a cool, dry place away from direct light. It is best kept in a sealed, airtight container to maintain its stability. The recommended storage temperature is between 15°C and 25°C, with controlled humidity levels to prevent degradation.