2-Phenylimidazo[1,2-a]pyridine

Basic Information

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CAS Number

4105-21-9

Molecular Formula

C13H10N2

Molecular Weight

194.24 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

133.0 to 137.0 deg-C

Boiling Point

245°C/11mmHg

SMILES

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C1=CC=C(C=C1)C2=CN3C=CC=CC3=N2

InChI

InChI=1S/C13H10N2/c1-2-6-11(7-3-1)12-10-15-9-5-4-8-13(15)14-12/h1-10H

InChIKey

KDHWCFCNNGUJCP-UHFFFAOYSA-N

LogP

3.0013000000000014

Topological Polar Surface Area

17.3 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

211

Synonyms & References

English

doi:10.14272/KDHWCFCNNGUJCP-UHFFFAOYSA-N.1
BDBM50269841
IMIDAZO[1,2-A]PYRIDINE, 2-PHENYL-
SMR000060551
KDHWCFCNNGUJCP-UHFFFAOYSA-N
Oprea1_695181
NSC-77913
10.14272/KDHWCFCNNGUJCP-UHFFFAOYSA-N.1
AKOS000416646
SR-01000638986-1
MLS002694050
CS-0126878
4105-21-9
2-Phenyl-imidazo[1,2-a]pyridine
NSC77913
CHEMBL1720835
EU-0077265
A21136
2-phenylimidazo[1,2-a]pyridine
Maybridge1_004380
FT-0760695
F1550-0046
HMS553P04
HMS3087C06
AB04929
AF-964/00531022
SCHEMBL966793
GS-5443
P2632
DTXSID10276799
SY235180

MDL Number

MFCD00219254

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 2-Phenylimidazo[1,2-a]pyridine (CAS: 4105-21-9)?

2-Phenylimidazo[1,2-a]pyridine is a crystalline solid with a molecular weight of approximately 182.21 g/mol. It is slightly soluble in water but more soluble in organic solvents like ethanol and acetone. Chemically, it is moderately reactive towards nucleophiles and exhibits good stability under normal conditions. It is also known to have some photochemical and electrochemical properties.

How is 2-Phenylimidazo[1,2-a]pyridine (CAS: 4105-21-9) typically synthesized?

2-Phenylimidazo[1,2-a]pyridine is typically synthesized via the condensation of 2-bromopyridine and aniline using a suitable base like sodium hydride as a catalyst. The reaction proceeds under mild conditions, yielding a product with high selectivity. The overall yield is around 70-80%.

What industries use 2-Phenylimidazo[1,2-a]pyridine (CAS: 4105-21-9)?

2-Phenylimidazo[1,2-a]pyridine finds applications in the pharmaceutical industry as a potential anti-inflammatory agent and in the polymer industry as a stabilizer. It is also used in the development of sensors and as a precursor for organic electronics and semiconductors.

What precautions should be taken when handling 2-Phenylimidazo[1,2-a]pyridine (CAS: 4105-21-9)?

When handling 2-Phenylimidazo[1,2-a]pyridine, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize exposure. Spills should be cleaned up using appropriate absorbents and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.