Ethyl (trimethylsilyl)acetate

Basic Information

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CAS Number

4071-88-9

Molecular Formula

C7H16O2Si

Molecular Weight

160.29 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Physical Properties

Boiling Point

159°C

Refractive Index

n20/D 1.415(lit.)

SMILES

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CCOC(=O)C[Si](C)(C)C

InChI

InChI=1S/C7H16O2Si/c1-5-9-7(8)6-10(2,3)4/h5-6H2,1-4H3

InChIKey

QQFBQBDINHJDMN-UHFFFAOYSA-N

LogP

1.8877

Topological Polar Surface Area

26.3 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

115

Safety Information

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GHS Hazard Pictograms

H226

Hazard Statement

H226 Flammable liquid and vapor
Flammable liquids

Hazard Class

Class 3 Class 3

Sensitiveness

Moisture Sensitive

Synonyms & References

English

NSC-108051
Ethyltrimethylsilylacetate
Ethyl 2-(trimethylsilyl)acetate
Ethyl (trimethylsilyl)acetate
AKOS015909085
Ethyl trimethylsilylacetate, purum, >=95.0% (GC)
(Trimethylsilyl)acetic Acid Ethyl Ester
QQFBQBDINHJDMN-UHFFFAOYSA-
NSC234752
InChI=1/C7H16O2Si/c1-5-9-7(8)6-10(2,3)4/h5-6H2,1-4H3
JJ5WZD3DYT
MFCD00009172
NSC 108051
T1584
ethyl(trimethylsilyl)acetate
Ethyl2-(trimethylsilyl)acetate
SCHEMBL435045
ethyl 2-trimethylsilylacetate
trimethylsilanyl-acetic acid ethyl ester
CS-W016151
ethyl trimethlysilylacetate
UNII-JJ5WZD3DYT
4071-88-9
Ethyl trimethylsilylacetate, >=98%
Ethyl(2-trimethylsilyl)acetate
DTXSID10193694
Ethyl (2-trimethylsilyl)-acetate
EINECS 223-783-2
NSC108051
CS-17372
trimethylsilylacetic acid ethyl ester

MDL Number

MFCD00009172

Customs Code

2931900090

FAQ

What are the physical and chemical properties of Ethyl (trimethylsilyl)acetate (CAS: 4071-88-9)?

Ethyl (trimethylsilyl)acetate (CAS: 4071-88-9) is a colorless liquid with a fruity odor. It has a molecular weight of approximately 171.26 g/mol and a boiling point of 101°C. The compound is moderately soluble in water but miscible with a variety of organic solvents. It is relatively stable under normal conditions but may react with strong bases to form silanols.

How is Ethyl (trimethylsilyl)acetate (CAS: 4071-88-9) typically synthesized?

Ethyl (trimethylsilyl)acetate (CAS: 4071-88-9) is usually synthesized by the reaction of ethyl acetate with trimethylsilyl chloride in the presence of a Lewis acid catalyst, such as aluminum chloride. The reaction is typically performed under anhydrous conditions to ensure high yield and selectivity.

What industries use Ethyl (trimethylsilyl)acetate (CAS: 4071-88-9)?

Ethyl (trimethylsilyl)acetate (CAS: 4071-88-9) is widely used in the pharmaceutical industry for intermediate synthesis, in polymer production for modifying properties, in sensor technology for detecting organic compounds, and in semiconductor manufacturing as a cleaning agent due to its inert nature and low toxicity.

What precautions should be taken when handling Ethyl (trimethylsilyl)acetate (CAS: 4071-88-9)?

When handling Ethyl (trimethylsilyl)acetate (CAS: 4071-88-9), wear appropriate personal protective equipment (PPE) including gloves, safety goggles, and a lab coat. Use in a well-ventilated area or a fume hood to avoid inhalation. Store the compound at room temperature away from heat sources and incompatible materials. In case of a spill, use appropriate absorbents and consult the Safety Data Sheet (SDS) for more detailed handling instructions.