Ethyl (trimethylsilyl)acetate(CAS: 4071-88-9)

Ethyl (trimethylsilyl)acetate (CAS: 4071-88-9) is a colorless liquid with a fruity odor. It has a molecular weight of approximately 171.26 g/mol and a boiling point of 101°C. The compound is moderately soluble in water but miscible with a variety of organic solvents. It is relatively stable under normal conditions but may react with strong bases to form silanols.

Ethyl (trimethylsilyl)acetate (CAS: 4071-88-9) is usually synthesized by the reaction of ethyl acetate with trimethylsilyl chloride in the presence of a Lewis acid catalyst, such as aluminum chloride. The reaction is typically performed under anhydrous conditions to ensure high yield and selectivity.

Ethyl (trimethylsilyl)acetate (CAS: 4071-88-9) is widely used in the pharmaceutical industry for intermediate synthesis, in polymer production for modifying properties, in sensor technology for detecting organic compounds, and in semiconductor manufacturing as a cleaning agent due to its inert nature and low toxicity.

When handling Ethyl (trimethylsilyl)acetate (CAS: 4071-88-9), wear appropriate personal protective equipment (PPE) including gloves, safety goggles, and a lab coat. Use in a well-ventilated area or a fume hood to avoid inhalation. Store the compound at room temperature away from heat sources and incompatible materials. In case of a spill, use appropriate absorbents and consult the Safety Data Sheet (SDS) for more detailed handling instructions.