(3,4-Dimethoxyphenyl)(phenyl)methanone

Basic Information

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CAS Number

4038-14-6

Molecular Formula

C15H14O3

Molecular Weight

242.27 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

100-102°C

Boiling Point

380.7 ℃ at 760 mmHg

SMILES

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COC1=C(C=C(C=C1)C(=O)C2=CC=CC=C2)OC

InChI

InChI=1S/C15H14O3/c1-17-13-9-8-12(10-14(13)18-2)15(16)11-6-4-3-5-7-11/h3-10H,1-2H3

InChIKey

WCNOATOQNSHEFK-UHFFFAOYSA-N

LogP

2.934800000000001

Topological Polar Surface Area

35.53 Å²

Hydrogen Bond Donor/Acceptor

0 / 3

Complexity

271

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

PS-5008
NSC145888
(3,4-Dimethoxyphenyl)(Phenyl)Methanone
(3,4-Dimethoxyphenyl)phenylmethanone
AMY11231
MFCD00075875
FT-0653620
(3,4-Dimethoxyphenyl)-phenyl-methanone
(3,4-dimethoxyphenyl)-phenylmethanone
H10714
(3,4-Dimethoxy-phenyl)-phenyl-methanone
Oprea1_124417
SY018969
DTXSID40301689
AKOS000277595
CHEMBL1171353
Methanone, (3,4-dimethoxyphenyl)phenyl-
AE-641/00008053
(3,4-Dimethoxyphenyl)-phenyl-methanon
SCHEMBL1333620
3,4-dimethoxy benzophenone
3,4-DIMETHOXYBENZOPHENONE
Oprea1_625204
CS-0150592
4038-14-6
NSC-145888
(3,4-Dimethoxyphenyl)(phenyl)methanone
(3,4-DIMETHOXY-PHENYL)-PHENYL-METHANONE
3,4-Dimethoxy benzophenone
3,4-Dimethoxy-benzophenon
3,4-dimethoxyphenyl phenyl ketone

MDL Number

MFCD00075875

Customs Code

2914509090

FAQ

What are the physical and chemical properties of (3,4-Dimethoxyphenyl)(phenyl)methanone (CAS: 4038-14-6)?

(3,4-Dimethoxyphenyl)(phenyl)methanone is a white crystalline solid with a molecular weight of approximately 260.24 g/mol. It has a low solubility in water (0.04 g/100 mL at 25°C) and good solubility in organic solvents such as methanol, ethanol, and dichloromethane. This compound is relatively stable but can react with strong acids or bases. It is not flammable and has a melting point around 128-130°C. For storage and handling, it is recommended to keep in a cool, dry place away from direct sunlight.

How is (3,4-Dimethoxyphenyl)(phenyl)methanone (CAS: 4038-14-6) typically synthesized?

(3,4-Dimethoxyphenyl)(phenyl)methanone can be synthesized through a condensation reaction between 3,4-dimethoxyphenylacetic acid and phenylmagnesium bromide in an anhydrous solvent like THF. The reaction typically requires a Lewis acid catalyst, such as boron trifluoride etherate, to enhance the reactivity. The yield is usually around 70-80% with good selectivity towards the desired product. This synthesis is performed under inert conditions to avoid oxidation or deprotection of the sensitive methoxy groups.

What industries use (3,4-Dimethoxyphenyl)(phenyl)methanone (CAS: 4038-14-6)?

(3,4-Dimethoxyphenyl)(phenyl)methanone is used in various industries, particularly in the pharmaceutical and polymer sectors. In the pharmaceutical industry, it serves as a key intermediate in the synthesis of certain drugs. In polymer manufacturing, it can be used as a monomer or additive to enhance properties like flexibility and thermal stability. Additionally, it has applications in the production of sensors and semiconductors given its electronic properties.

What precautions should be taken when handling (3,4-Dimethoxyphenyl)(phenyl)methanone (CAS: 4038-14-6)?

When handling (3,4-Dimethoxyphenyl)(phenyl)methanone, it is important to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. This compound should be stored in a cool, dry place away from direct sunlight and flammable materials. Spills should be cleaned up using absorbent materials and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures. The compound is non-toxic by oral ingestion but may cause skin irritation; immediate medical attention should be sought if exposure occurs.