(2,4-Dichloro-5-isopropoxyphenyl)hydrazine

Basic Information

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CAS Number

40178-22-1

Molecular Formula

C9H12Cl2N2O

Molecular Weight

235.11 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Boiling Point

319.9°Cat760mmHg

Flash Point

147.3°C

Refractive Index

1.597

SMILES

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CC(C)OC1=C(C=C(C(=C1)NN)Cl)Cl

InChI

InChI=1S/C9H12Cl2N2O/c1-5(2)14-9-4-8(13-12)6(10)3-7(9)11/h3-5,13H,12H2,1-2H3

InChIKey

GWHQKTAGVTYTJX-UHFFFAOYSA-N

LogP

3.0661999999999994

Topological Polar Surface Area

47.28 Å²

Hydrogen Bond Donor/Acceptor

3 / 3

Complexity

180

Synonyms & References

English

40178-22-1
CS-0452133
EINECS 254-824-2
2,4-dichloro-5-(1-methylethoxy)phenylhydrazine
A6717
NS00030735
GWHQKTAGVTYTJX-UHFFFAOYSA-N
AKOS015890646
1-(2,4-dichloro-5-isopropoxyphenyl)hydrazine
SB80657
(2,4-dichloro-5-propan-2-yloxyphenyl)hydrazine
2,4-DICHLORO-5-(1-METHYLETHOXY)PHENYLHYDRAZIN
FT-0657613
DTXSID20193180
(2,4-Dichloro-5-isopropoxyphenyl)hydrazine
Hydrazine, [2,4-dichloro-5-(1-methylethoxy)phenyl]-
SCHEMBL9664584
2,4-Dichloro-5-(1-methylethoxy)phenylhydrazine
Hydrazine, [2,4-dichloro-5-(1-Methylethoxy)phenyl]-
2,4-Dichloro-5-(1-methylethoxy)phenylhydrazin

MDL Number

MFCD10000641

FAQ

What are the physical and chemical properties of (2,4-Dichloro-5-isopropoxyphenyl)hydazine (CAS: 40178-22-1)?

(2,4-Dichloro-5-isopropoxyphenyl)hydazine is a crystalline solid with a molecular weight of approximately 347.03 g/mol. It has a low solubility in water (0.017 g/100 mL at 20°C) and is soluble in organic solvents like methanol and ethanol. This compound is relatively stable but can react with strong acids or bases to form undesired products. It is used as an intermediate in the synthesis of other compounds, and proper handling and storage are essential to prevent degradation.

How is (2,4-Dichloro-5-isopropoxyphenyl)hydazine (CAS: 40178-22-1) typically synthesized?

(2,4-Dichloro-5-isopropoxyphenyl)hydazine can be synthesized via the reduction of the corresponding nitro compound, often using a hydrogenation catalyst like palladium on carbon. The process typically involves the use of a solvent such as methanol or ethanol, and the reaction is carried out under hydrogen pressure. The yield is usually between 70-85%, and the selectivity is high, with minimal formation of by-products.

What industries use (2,4-Dichloro-5-isopropoxyphenyl)hydazine (CAS: 40178-22-1)?

(2,4-Dichloro-5-isopropoxyphenyl)hydazine is primarily used as an intermediate in the pharmaceutical and fine chemical industries. It serves as a key building block in the synthesis of various drug candidates and active pharmaceutical ingredients. Additionally, it may find applications in the polymer and semiconductor industries, although on a smaller scale compared to its pharmaceutical uses.

What precautions should be taken when handling (2,4-Dichloro-5-isopropoxyphenyl)hydazine (CAS: 40178-22-1)?

When handling (2,4-Dichloro-5-isopropoxyphenyl)hydazine, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, laboratory coat, and safety goggles. This compound should be stored in a cool, dry place away from direct sunlight and heat sources. In case of a spill, the area should be ventilated, and the spill should be contained and disposed of according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed information on handling and storage.