5-[2-Cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetate hydrochloride (1:1) | CAS No. 389574-19-0
5-[2-Cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetate hydrochloride (1:1)
Basic Information
CAS Number
389574-19-0
Molecular Formula
C20H21ClFNO3S
Molecular Weight
409.91 g/mol
AD
Chemical Classification
Basic Physical Properties
Synonyms & References
English
- Effient (TN)
- (+-)-prasugrel hydrochloride
- s4637
- PCR 4099 (hydrochloride)
- LY640315
- rac-2-(acetyloxy)-5-(2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl)-4,5,6,7-tetrahydrothieno(3,2-c)pyridin-5-ium chloride
- Prasugrenhydrochloride
- Prasugrel HCl
- PRASUGREL HYDROCHLORIDE [ORANGE BOOK]
- MFCD11867705
- 2-ACETOXY-5-(alpha-CYCLOPROPYLCARBONYL-2-FLUOROBENZYL)-4,5,6,7-TETRAHYDROTHIENO(3,2-C)PYRIDINE HYDROCHLORIDE
- Effient hydrochloride
- PRASUGREL HYDROCHLORIDE [USP MONOGRAPH]
- Q27278929
- Prasugren HCl
- rac-prasugrel hydrochloride
- (RS)-prasugrel hydrochloride
- HCl, Prasugrel
- HY-15284A
- CCG-268764
- NCGC00188690-01
- PRASUGREL HYDROCHLORIDE [VANDF]
- CHEMBL1201773
- CHEBI:87697
- 5-((1RS)-2-Cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl)-4,5,6,7-tetrahydrothieno(3,2-c)pyridin-2-yl acetate monohydrochloride
- BCP16928
- 5-(2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetate hydrochloride
- Prasugrel (hydrochloride)
- PRASUGREL HYDROCHLORIDE (USP-RS)
- Ethanone, 2-(2-(acetyloxy)-6,7-dihydrothieno(3,2-c)pyridin-5(4H)-yl)-1-cyclopropyl-2-(2-fluorophenyl)-, hydrochloride
- PRASUGREL HYDROCHLORIDE (EP MONOGRAPH)
MDL Number
MFCD11867705
FAQ
What are the physical and chemical properties of 5-[2-Cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetate hydrochloride (CAS: 389574-19-0)?
This compound is a crystalline solid with a molecular weight of approximately 523.66 g/mol. It has a low solubility in water but is more soluble in organic solvents like dimethylformamide (DMF) and methanol. The compound exhibits moderate reactivity, particularly in acidic conditions. It is highly sensitive to moisture and heat, requiring careful handling to prevent degradation.
How is 5-[2-Cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetate hydrochloride (CAS: 389574-19-0) typically synthesized?
The compound is synthesized using a multistep process involving the condensation of a fluorophenyl-substituted cyclopropylacetic acid derivative with a thieno[3,2-c]pyridine intermediate under basic conditions. The final step involves acetonylation followed by hydrochloride salt formation. The reaction is typically catalyzed by a mild base like triethylamine, and the selectivity and yield are high due to optimized reaction conditions.
What industries use 5-[2-Cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetate hydrochloride (CAS: 389574-19-0)?
This compound is primarily used in the pharmaceutical industry as an intermediate in the synthesis of complex drugs. It also has potential applications in the development of novel materials, particularly in the polymer and sensor sectors, due to its unique structural features.
What precautions should be taken when handling 5-[2-Cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetate hydrochloride (CAS: 389574-19-0)?
When handling this compound, it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated hood to minimize exposure. The compound should be stored in a cool, dry place away from moisture and heat. In case of a spill, neutralize the spill with an appropriate solvent and dispose of the waste according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed handling and safety information.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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