5-[2-Cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetate hydrochloride (1:1)(CAS: 389574-19-0)

This compound is a crystalline solid with a molecular weight of approximately 523.66 g/mol. It has a low solubility in water but is more soluble in organic solvents like dimethylformamide (DMF) and methanol. The compound exhibits moderate reactivity, particularly in acidic conditions. It is highly sensitive to moisture and heat, requiring careful handling to prevent degradation.

The compound is synthesized using a multistep process involving the condensation of a fluorophenyl-substituted cyclopropylacetic acid derivative with a thieno[3,2-c]pyridine intermediate under basic conditions. The final step involves acetonylation followed by hydrochloride salt formation. The reaction is typically catalyzed by a mild base like triethylamine, and the selectivity and yield are high due to optimized reaction conditions.

This compound is primarily used in the pharmaceutical industry as an intermediate in the synthesis of complex drugs. It also has potential applications in the development of novel materials, particularly in the polymer and sensor sectors, due to its unique structural features.

When handling this compound, it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated hood to minimize exposure. The compound should be stored in a cool, dry place away from moisture and heat. In case of a spill, neutralize the spill with an appropriate solvent and dispose of the waste according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed handling and safety information.