5,7-Dimethoxy-2-(4-methoxyphenyl)-2,3-dihydro-4H-chromen-4-one | CAS No. 38302-15-7

5,7-Dimethoxy-2-(4-methoxyphenyl)-2,3-dihydro-4H-chromen-4-one

Basic Information

CAS Number

38302-15-7

Molecular Formula

C18H18O5

Molecular Weight

314.34 g/mol

AD

Basic Physical Properties

Physical State

Powder

COc1ccc(cc1)C2CC(=O)c3c(cc(cc3OC)OC)O2

InChI

InChI=1S/C18H18O5/c1-20-12-6-4-11(5-7-12)15-10-14(19)18-16(22-3)8-13(21-2)9-17(18)23-15/h4-9,15H,10H2,1-3H3

InChIKey

MQFSCAHSIUPLSB-UHFFFAOYSA-N

LogP

3.4189000000000025

Topological Polar Surface Area

53.99000000000001 Ų

Hydrogen Bond Donor/Acceptor

0 / 5

Complexity

404

Synonyms & References

English

  • 5,7-Dimethoxy-2-(4-methoxyphenyl)chroman-4-one
  • Naringenin trimethyl ether
  • [ "4'", "5", "7-Trimethoxyflavanone" ]
  • 5,7,4'-Trimethoxyflavanone
  • 5,7-dimethoxy-2-(4-methoxyphenyl)-2,3-dihydrochromen-4-one
  • 4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dimethoxy-2-(4-methoxyphenyl)-
  • Oprea1_436908
  • 4',5,7-Trimethoxyflavanone
  • 5, 4' Trimethoxy Flavanone
  • MQFSCAHSIUPLSB-UHFFFAOYSA-N
  • NSC735006
  • LMPK12140596
  • 4',5,7-trimethoxyflavanone, AldrichCPR
  • AK104323
  • ST24044124
  • W1578
  • ST2404412

MDL Number

MFCD20260482

Customs Code

2932999099

FAQ

What are the physical and chemical properties of 5,7-Dimethoxy-2-(4-methoxyphenyl)-2,3-dihydro-4H-chromen-4-one (CAS: 38302-15-7)?

5,7-Dimethoxy-2-(4-methoxyphenyl)-2,3-dihydro-4H-chromen-4-one is a white to off-white crystalline solid with a molecular weight of approximately 326.35 g/mol. It has a solubility of about 0.1 g/L in water and is generally less reactive than many other chromones. It dissolves readily in organic solvents like ethanol and acetone. It is stable under normal atmospheric conditions but should be stored in a cool, dry place to prevent degradation.

How is 5,7-Dimethoxy-2-(4-methoxyphenyl)-2,3-dihydro-4H-chromen-4-one (CAS: 38302-15-7) typically synthesized?

5,7-Dimethoxy-2-(4-methoxyphenyl)-2,3-dihydro-4H-chromen-4-one is typically synthesized via a multistep process involving protection of an alcohol group, followed by a condensation reaction between an aldehyde and a phenol derivative. The reaction proceeds under basic conditions, and the yield is around 70-80% with good selectivity. Suitable catalysts include sodium hydroxide and potassium hydroxide.

What industries use 5,7-Dimethoxy-2-(4-methoxyphenyl)-2,3-dihydro-4H-chromen-4-one (CAS: 38302-15-7)?

5,7-Dimethoxy-2-(4-methoxyphenyl)-2,3-dihydro-4H-chromen-4-one is used in the pharmaceutical industry as an intermediate in the synthesis of certain drugs due to its structural complexity. It is also utilized in the polymer industry for the preparation of functionalized polymers with specific properties. Additionally, it finds application in the development of sensors and semiconductors for its unique electronic and optical properties.

What precautions should be taken when handling 5,7-Dimethoxy-2-(4-methoxyphenyl)-2,3-dihydro-4H-chromen-4-one (CAS: 38302-15-7)?

When handling 5,7-Dimethoxy-2-(4-methoxyphenyl)-2,3-dihydro-4H-chromen-4-one, it is important to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. It should be stored in a cool, dry place, and the storage area should be well-ventilated. In case of a spill, it should be cleaned up using appropriate absorbent materials and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.

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