5,7-Dimethoxy-2-(4-methoxyphenyl)-2,3-dihydro-4H-chromen-4-one(CAS: 38302-15-7)

5,7-Dimethoxy-2-(4-methoxyphenyl)-2,3-dihydro-4H-chromen-4-one is a white to off-white crystalline solid with a molecular weight of approximately 326.35 g/mol. It has a solubility of about 0.1 g/L in water and is generally less reactive than many other chromones. It dissolves readily in organic solvents like ethanol and acetone. It is stable under normal atmospheric conditions but should be stored in a cool, dry place to prevent degradation.

5,7-Dimethoxy-2-(4-methoxyphenyl)-2,3-dihydro-4H-chromen-4-one is typically synthesized via a multistep process involving protection of an alcohol group, followed by a condensation reaction between an aldehyde and a phenol derivative. The reaction proceeds under basic conditions, and the yield is around 70-80% with good selectivity. Suitable catalysts include sodium hydroxide and potassium hydroxide.

5,7-Dimethoxy-2-(4-methoxyphenyl)-2,3-dihydro-4H-chromen-4-one is used in the pharmaceutical industry as an intermediate in the synthesis of certain drugs due to its structural complexity. It is also utilized in the polymer industry for the preparation of functionalized polymers with specific properties. Additionally, it finds application in the development of sensors and semiconductors for its unique electronic and optical properties.

When handling 5,7-Dimethoxy-2-(4-methoxyphenyl)-2,3-dihydro-4H-chromen-4-one, it is important to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. It should be stored in a cool, dry place, and the storage area should be well-ventilated. In case of a spill, it should be cleaned up using appropriate absorbent materials and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.