2-Amino-5-bromophenol

Basic Information

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CAS Number

38191-34-3

Molecular Formula

C6H6BrNO

Molecular Weight

188.02 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Boiling Point

265°C at 760 mmHg

Flash Point

114.096℃

SMILES

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Nc1ccc(Br)cc1O

InChI

InChI=1S/C6H6BrNO/c7-4-1-2-5(8)6(9)3-4/h1-3,9H,8H2

InChIKey

DRQWUAAWZFIVTF-UHFFFAOYSA-N

LogP

1.7368999999999999

Topological Polar Surface Area

46.25 Å²

Hydrogen Bond Donor/Acceptor

3 / 2

Complexity

99.1

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H332 Harmful if inhaled
Acute toxicity, inhalation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

2-Amino-5-bromophenol
2-AMino-5-broMphenol
4-Bromo-2-hydroxyaniline
4-Bromo-2-hydroxylaniline
4-Bromo-2-hydroxylbenzenamine
C6H6BrNO
2-amino 5-bromophenol
PHENOL, 2-AMINO-5-BROMO-
PubChem10469
5-bromo-2-aminophenol
2-Amino-5-bromo-phenol
4-bromo-2-hydroxy-aniline
KSC497M1B
EBD6946
DRQWUAAWZFIVTF-UHFFFAOYSA-N
WT682
BCP22833
2-Amino-5-bromophenol, AldrichCPR
STL557665
SBB051770
RW3512
BBL103855
AB13424
TRA0039308
LS10644
2-amino-5-bromophenol

MDL Number

MFCD03095028

Customs Code

2922299090

FAQ

What are the physical and chemical properties of 2-Amino-5-bromophenol (CAS: 38191-34-3)?

2-Amino-5-bromophenol (CAS: 38191-34-3) is a white crystalline solid with a molecular weight of approximately 221.02 g/mol. It has a solubility of about 3.8 g/L in water at 20°C. Chemically, it is moderately reactive, particularly towards nucleophilic substitution reactions. It dissolves well in polar solvents such as ethanol and methanol.

How is 2-Amino-5-bromophenol (CAS: 38191-34-3) typically synthesized?

2-Amino-5-bromophenol can be synthesized by bromination of 5-aminophenol followed by purification. Commonly, this involves the reaction of 5-aminophenol with bromine in the presence of a Lewis acid catalyst such as iron(III) bromide. The yield is typically around 70-85%, and the reaction provides a selective route to the target compound.

What industries use 2-Amino-5-bromophenol (CAS: 38191-34-3)?

2-Amino-5-bromophenol is used in various industries. It is a key intermediate in pharmaceuticals, where it is used to synthesize certain drugs. It also finds applications in the polymer industry for the production of certain resins and adhesives. Additionally, it is used in the development of sensors and in electronic applications due to its unique chemical properties.

What precautions should be taken when handling 2-Amino-5-bromophenol (CAS: 38191-34-3)?

When handling 2-Amino-5-bromophenol (CAS: 38191-34-3), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a fume hood to minimize inhalation risk. Spills should be cleaned up using appropriate absorbent materials and proper disposal methods. Refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.