2-Amino-5-bromophenol(CAS: 38191-34-3)

2-Amino-5-bromophenol (CAS: 38191-34-3) is a white crystalline solid with a molecular weight of approximately 221.02 g/mol. It has a solubility of about 3.8 g/L in water at 20°C. Chemically, it is moderately reactive, particularly towards nucleophilic substitution reactions. It dissolves well in polar solvents such as ethanol and methanol.

2-Amino-5-bromophenol can be synthesized by bromination of 5-aminophenol followed by purification. Commonly, this involves the reaction of 5-aminophenol with bromine in the presence of a Lewis acid catalyst such as iron(III) bromide. The yield is typically around 70-85%, and the reaction provides a selective route to the target compound.

2-Amino-5-bromophenol is used in various industries. It is a key intermediate in pharmaceuticals, where it is used to synthesize certain drugs. It also finds applications in the polymer industry for the production of certain resins and adhesives. Additionally, it is used in the development of sensors and in electronic applications due to its unique chemical properties.

When handling 2-Amino-5-bromophenol (CAS: 38191-34-3), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a fume hood to minimize inhalation risk. Spills should be cleaned up using appropriate absorbent materials and proper disposal methods. Refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.