5-Bromo-3-chloro-2-pyridinamine

Basic Information

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CAS Number

38185-55-6

Molecular Formula

C5H4BrClN2

Molecular Weight

207.46 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Boiling Point

232.5℃ at 760 mmHg

SMILES

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C1=C(C=NC(=C1Cl)N)Br

InChI

InChI=1S/C5H4BrClN2/c6-3-1-4(7)5(8)9-2-3/h1-2H,(H2,8,9)

InChIKey

VXCUGLKQXLPHKI-UHFFFAOYSA-N

LogP

2.0797

Topological Polar Surface Area

38.91 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

101

Synonyms & References

English

FT-0767445
SCHEMBL122355
J-517015
BCP22849
EN300-107949
TS-02964
DTXSID80494802
2-AMINO-5-BROMO-3-CHLOROPYRIDINE
2-Pyridinamine,5-bromo-3-chloro-
J-803026
38185-55-6
SY047628
A824043
VXCUGLKQXLPHKI-UHFFFAOYSA-N
CS-W008920
AM86921
5-bromo-3-chloro-2-pyridinamine
AB63574
AC-28018
P11078
5-bromo-3-chloropyridin-2-amine
5-Bromo-3-chloro-pyridin-2-ylamine
BCP9000089
5-bromo-3-chloropyridine-2-amine
5-bromanyl-3-chloranyl-pyridin-2-amine
2-PYRIDINAMINE, 5-BROMO-3-CHLORO-
AKOS015891867
MFCD11110443
2-Amino-3-chloro-5-bromopyridine
2-Amino-5-bromo-3-chloropyridine
5-Bromo-3-chloropyridin-2-amine

MDL Number

MFCD11110443

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 5-Bromo-3-chloro-2-pyridinamine (CAS: 38185-55-6)?

5-Bromo-3-chloro-2-pyridinamine is a crystalline solid with a molecular weight of approximately 218.01 g/mol. It is slightly soluble in water and more soluble in organic solvents like methanol and ethanol. This compound exhibits moderate reactivity and is susceptible to hydrolysis under basic conditions. It is typically stored at room temperature away from moisture and heat.

How is 5-Bromo-3-chloro-2-pyridinamine (CAS: 38185-55-6) typically synthesized?

5-Bromo-3-chloro-2-pyridinamine is often synthesized via the condensation of 3-chloro-2-pyridinamine with bromine in the presence of a base. The reaction is typically carried out in a polar aprotic solvent like acetonitrile. The yield is around 70-80%, and the product is isolated via recrystallization from a suitable solvent.

What industries use 5-Bromo-3-chloro-2-pyridinamine (CAS: 38185-55-6)?

5-Bromo-3-chloro-2-pyridinamine is used in the pharmaceutical industry for the synthesis of various drug intermediates. It is also employed in the polymer industry for the development of functional polymers and in the sensor industry for the fabrication of gas sensors. Additionally, it has applications in semiconductor manufacturing for doping materials.

What precautions should be taken when handling 5-Bromo-3-chloro-2-pyridinamine (CAS: 38185-55-6)?

Proper personal protective equipment (PPE) must be worn when handling 5-Bromo-3-chloro-2-pyridinamine, including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated fume hood. Spills should be cleaned up using an appropriate absorbent material and disposed of according to local regulations. Always refer to the safety data sheet (SDS) for specific handling and disposal instructions.