N1-(Adamantan-1-yl)ethane-1,2-diamine

Basic Information

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CAS Number

37818-93-2

Molecular Formula

C12H22N2

Molecular Weight

194.32 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Physical Properties

Refractive Index

1.5220-1.5250

SMILES

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NCCNC12CC3CC(C2)CC(C3)C1

InChI

InChI=1S/C12H22N2/c13-1-2-14-12-6-9-3-10(7-12)5-11(4-9)8-12/h9-11,14H,1-8,13H2

InChIKey

IQMUFNISQFPZJC-UHFFFAOYSA-N

LogP

1.5034999999999992

Topological Polar Surface Area

38.05 Å²

Hydrogen Bond Donor/Acceptor

3 / 2

Complexity

183

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

N1-(Adamantan-1-yl)ethane-1,2-diamine
N-(1-Adamantyl)ethylenediamine
N'-(1-adamantyl)ethane-1,2-diamine
1-[N-(2-Aminoethyl)amino]adamantane
adamantanyl(2-aminoethyl)amine
N-(1-Adamantyl)-ethylendiamin
NSC 193472
N-Tricyclo[3.3.1.1(3,7)]dec-1-yl-1,2-ethanediamine
N-(2-aminoethyl)adamantan-1-amine
NSC193472
adamantyl-ethylenediamine
TimTec1_002953
Oprea1_805375
HMS1542G05
ZERO/001765
STK678200
SBB012661
TRA0016868
ST038845
AK1

MDL Number

MFCD02093421

Customs Code

2921300090

FAQ

What are the physical and chemical properties of N1-(Adamantan-1-yl)ethane-1,2-diamine (CAS: 37818-93-2)?

N1-(Adamantan-1-yl)ethane-1,2-diamine (CAS: 37818-93-2) is a colorless liquid with a molecular weight of approximately 210.35 g/mol. It is soluble in common organic solvents like ethanol and dimethylformamide. The compound is moderately reactive, showing basic properties due to the amine groups, which can react with acids to form salts. It has a characteristic odor similar to adamantane.

How is N1-(Adamantan-1-yl)ethane-1,2-diamine (CAS: 37818-93-2) typically synthesized?

N1-(Adamantan-1-yl)ethane-1,2-diamine (CAS: 37818-93-2) is typically synthesized through the reaction of 1-adamantanamine with ethyl chloroacetate in the presence of a base like sodium hydride. The process involves the nucleophilic substitution of the chlorine atom by the amino group, followed by the deprotonation and subsequent cyclization to form the desired diamine. The reaction is carried out under mild conditions to ensure high selectivity and yield.

What industries use N1-(Adamantan-1-yl)ethane-1,2-diamine (CAS: 37818-93-2)?

N1-(Adamantan-1-yl)ethane-1,2-diamine (CAS: 37818-93-2) finds applications in pharmaceuticals for the synthesis of certain heterocycles and in the development of new drugs. It is also used in the polymer industry for the preparation of high-performance polymers, in sensors for its ability to interact with specific molecules, and in semiconductor production as a precursor for metal complexes.

What precautions should be taken when handling N1-(Adamantan-1-yl)ethane-1,2-diamine (CAS: 37818-93-2)?

When handling N1-(Adamantan-1-yl)ethane-1,2-diamine (CAS: 37818-93-2), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Spills should be handled in a well-ventilated area and with the use of a fume hood. In case of contact with skin or eyes, flush with copious amounts of water and seek medical attention. Always refer to the Safety Data Sheet (SDS) for detailed information on handling and storage. The compound is moderately reactive, so it should be stored in a cool, dry place away from strong acids and oxidizers.