How is N1-(Adamantan-1-yl)ethane-1,2-diamine (CAS: 37818-93-2) typically synthesized?

N1-(Adamantan-1-yl)ethane-1,2-diamine (CAS: 37818-93-2) is typically synthesized through the reaction of 1-adamantanamine with ethyl chloroacetate in the presence of a base like sodium hydride. The process involves the nucleophilic substitution of the chlorine atom by the amino group, followed by the deprotonation and subsequent cyclization to form the desired diamine. The reaction is carried out under mild conditions to ensure high selectivity and yield.