1-[4-(2-methylpropoxy)phenyl]methanamine hydrochloride | CAS No. 37806-44-3

1-[4-(2-methylpropoxy)phenyl]methanamine hydrochloride

Basic Information

CAS Number

37806-44-3

Molecular Formula

C11H18ClNO

Molecular Weight

215.72 g/mol

AD

Basic Physical Properties

Cl.CC(C)COc1ccc(CN)cc1

InChI

InChI=1S/C11H17NO.ClH/c1-9(2)8-13-11-5-3-10(7-12)4-6-11;/h3-6,9H,7-8,12H2,1-2H3;1H

InChIKey

BHKUKNJDPIWLRY-UHFFFAOYSA-N

LogP

2.6019000000000005

Topological Polar Surface Area

35.25 Ų

Hydrogen Bond Donor/Acceptor

2 / 2

Synonyms & References

English

  • 1-[4-(2-methylpropoxy)phenyl]methanamine hydrochloride
  • 4-(2-Methylpropoxy)benzenemethanamine hydrochloride

MDL Number

MFCD16605992

FAQ

What are the physical and chemical properties of 1-[4-(2-methylpropoxy)phenyl]methanamine hydrochloride (CAS: 37806-44-3)?

1-[4-(2-methylpropoxy)phenyl]methanamine hydrochloride has a crystalline form with a molecular weight of approximately 318.37 g/mol. It is moderately soluble in water and ethanol. The compound exhibits basic properties due to the presence of the hydrochloride ion, and it reacts with acids to form the free amine. It is stable under normal conditions but should be stored in a dry environment to prevent hydrolysis.

How is 1-[4-(2-methylpropoxy)phenyl]methanamine hydrochloride (CAS: 37806-44-3) typically synthesized?

1-[4-(2-methylpropoxy)phenyl]methanamine hydrochloride is synthesized through a multistep process involving the reaction of 2-methylpropanol with 4-chlorophenylmethanamine hydrochloride. The reaction is typically carried out in the presence of an acid catalyst such as sulfuric acid. The yield is around 85%, and the product is isolated by recrystallization from ethanol.

What industries use 1-[4-(2-methylpropoxy)phenyl]methanamine hydrochloride (CAS: 37806-44-3)?

1-[4-(2-methylpropoxy)phenyl]methanamine hydrochloride is primarily used in the pharmaceutical industry as an intermediate for drug synthesis. It has applications in the polymer industry as a stabilizer and in the semiconductor industry for the production of photoresists. Additionally, it is used in the sensor industry for the development of chemical sensors due to its reactivity.

What precautions should be taken when handling 1-[4-(2-methylpropoxy)phenyl]methanamine hydrochloride (CAS: 37806-44-3)?

When handling 1-[4-(2-methylpropoxy)phenyl]methanamine hydrochloride, appropriate personal protective equipment (PPE) should be worn, including gloves, eye protection, and a lab coat. This compound should be handled in a well-ventilated area or fume hood to prevent inhalation. Spills should be cleaned up with care, using appropriate absorbent materials, and the area should be flushed with water. Safety data sheets (SDS) should be consulted for detailed safety information and emergency procedures.

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