Compound Q&A

How is 1-[4-(2-methylpropoxy)phenyl]methanamine hydrochloride (CAS: 37806-44-3) typically synthesized?

Answer

1-[4-(2-methylpropoxy)phenyl]methanamine hydrochloride
1-[4-(2-methylpropoxy)phenyl]methanamine hydrochloride is synthesized through a multistep process involving the reaction of 2-methylpropanol with 4-chlorophenylmethanamine hydrochloride. The reaction is typically carried out in the presence of an acid catalyst such as sulfuric acid. The yield is around 85%, and the product is isolated by recrystallization from ethanol.

About

CAS No 37806-44-3
English Name 1-[4-(2-methylpropoxy)phenyl]methanamine hydrochloride
Molecular Formula C11H18ClNO
Molecular Weight 215.72 g/mol
SMILES Cl.CC(C)COc1ccc(CN)cc1
InChIKey BHKUKNJDPIWLRY-UHFFFAOYSA-N
Last Updated: 2025-11-27 19:31

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