Varenicline Tartrate

Basic Information

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CAS Number

375815-87-5

Molecular Formula

C17H19N3O6

Molecular Weight

361.35 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Physical State

Powder

Melting Point

206-208°C

Boiling Point

400.6°C at 760 mmHg

Flash Point

No data available

Solubility

DMSO: >5mg/mL

Vapor Pressure

No data available

SMILES

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C1C2CNCC1C3=CC4=NC=CN=C4C=C23.C(C(C(=O)O)O)(C(=O)O)O

InChI

InChI=1S/C13H13N3.C4H6O6/c1-2-16-13-5-11-9-3-8(6-14-7-9)10(11)4-12(13)15-1;5-1(3(7)8)2(6)4(9)10/h1-2,4-5,8-9,14H,3,6-7H2;1-2,5-6H,(H,7,8)(H,9,10)/t8-,9+;1-,2-/m.1/s1

InChIKey

TWYFGYXQSYOKLK-CYUSMAIQSA-N

LogP

-0.3186999999999993

Topological Polar Surface Area

152.87 Å²

Hydrogen Bond Donor/Acceptor

5 / 9

Complexity

388

Safety Information

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GHS Hazard Pictograms

H400

Hazard Statement

H400 Very toxic to aquatic life
Hazardous to the aquatic environment, acute hazard

Hazard Class

Class 9 Class 9

Synonyms & References

English

CS-0830
Tox21_500047
VARENICLINE TARTRATE (MART.)
(2R,3R)-2,3-dihydroxybutanedioic acid;5,8,14-triazatetracyclo[10.3.1.02,11.04,9]hexadeca-2,4,6,8,10-pentaene
Q27157813
Varenicline tartrate (JAN/USAN)
7,8,9,10-Tetrahydro-6H-6,10-methanoazepino(4,5-g)quinoxalinemono((2R,3R)-tartrate)
Varenicline tartrate
6,10-METHANO-6H-PYRAZINO(2,3-H)(3)BENZAZEPINE, 7,8,9,10-TETRAHYDRO-,(2R,3R)-2,3-DIHYDROXYBUTANEDIOATE (1:1)
7,8,9,10-tetrahydro-6H-6,10-methanoazepino(4,5-g)quinoxalin-8-ium (2R,3R)-3-carboxy-2,3-dihydroxypropanoate
Varenicline (Tartrate)
HB2070
7,8,9,10-Tetrahydro-6,10-methano-6H-pyrazino [2,3-h][3] benzazepine tartrate
375815-87-5
C13H13N3.C4H6O6
HMS3887M11
CHEMBL1201135
7,8,9,10-TETRAHYDRO-6, 10-METHANO-6H-PYRAZINA(2,3-H)(3)BENZAZEPINE, (2R,3R)-2,3-DIHYDROXYBUTANEDIOATE (1:1)
CP-526,555-18
7,8,9,10-tetrahydro-6H-6,10-methanoazepino[4,5-g]quinoxalin-8-ium (2R,3R)-3-carboxy-2,3-dihydroxypropanoate
Champix
SCHEMBL224852
CP 526555-18
7,8,9,10-Tetrahydro-6,10-methano-6H-pyrazino(2,3-h)(3)benzazepine (2R,3R)-2,3-dihydroxybutanedioate
TWYFGYXQSYOKLK-LREBCSMRSA-N
CCG-221351
Q-101415
varenicline monotartrate
D06282
7,8,9,10-tetrahydro-6H-6,10-methanoazepino[4,5-g]quinoxaline (2R,3R)-2,3-dihydroxysuccinic acid
Chantix (TN)

MDL Number

MFCD08460603

FAQ

What is Varenicline Tartrate (CAS: 375815-87-5)?

Varenicline Tartrate (CAS: 375815-87-5) is a pharmaceutical compound used primarily in smoking cessation treatments. It acts as a partial agonist at nicotinic acetylcholine receptors, helping to reduce nicotine cravings and withdrawal symptoms. Its chemical formula is C14H15NO3·C4H6O6, and it is a white to off-white powder with good solubility in water and alcohol.

What are the main uses of Varenicline Tartrate (CAS: 375815-87-5)?

Varenicline Tartrate (CAS: 375815-87-5) is mainly used in pharmaceuticals for smoking cessation therapy. It is also employed in research for studying nicotinic receptor interactions and in drug development for nicotine addiction treatments. Its applications include aiding patients in quitting smoking and supporting clinical studies on nicotine dependence.

Is Varenicline Tartrate (CAS: 375815-87-5) safe?

Varenicline Tartrate (CAS: 375815-87-5) is generally considered safe when used as directed in medical settings. However, it can cause side effects such as nausea, headache, and sleep disturbances. Proper handling and adherence to safety guidelines are essential, especially during storage and transportation. It is regulated by health authorities and must be used under professional supervision.

How should Varenicline Tartrate (CAS: 375815-87-5) be stored?

Varenicline Tartrate (CAS: 375815-87-5) should be stored in a cool, dry place away from direct light. It is typically kept at a temperature between 15°C to 25°C (59°F to 77°F) and in airtight containers to prevent moisture exposure. Proper storage ensures the stability and efficacy of the compound over time.