3-Bromo-4-(trifluoromethyl)benzaldehyde

Basic Information

View in Editor

CAS Number

372120-55-3

Molecular Formula

C8H4BrF3O

Molecular Weight

253.02 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Aldehydes

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

SMILES

View in Editor

C1=CC(=C(C=C1C=O)Br)C(F)(F)F

InChI

InChI=1S/C8H4BrF3O/c9-7-3-5(4-13)1-2-6(7)8(10,11)12/h1-4H

InChIKey

MWYYNBYTVFKXSD-UHFFFAOYSA-N

LogP

3.2804

Topological Polar Surface Area

17.07 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

192

Synonyms & References

English

3-Bromo-4-(trifluoromethyl)benzaldehyde
3-BROMO-4-TRIFLUOROMETHYLBENZALDEHYDE
CL8304
MWYYNBYTVFKXSD-UHFFFAOYSA-N
4750AB
PC10671
FCH1380605
AB0087417
AX8231713
ST24022728
3-Bromo-4-(trifluoromethyl)benzaldehyde, AldrichCPR
3-bromo-4-(trifluoromethyl)benzaldehyde
SCHEMBL7147339
XPA12055
AKOS015999915
SY046962
MFCD13185384
AMY38033
DB-165462
DTXSID60467317
AS-46015
CS-0097302
372120-55-3

MDL Number

MFCD13185384

Customs Code

2913000090

FAQ

What are the physical and chemical properties of 3-Bromo-4-(trifluoromethyl)benzaldehyde (CAS: 372120-55-3)?

3-Bromo-4-(trifluoromethyl)benzaldehyde (CAS: 372120-55-3) is a white crystalline solid with a molecular weight of approximately 260.03 g/mol. It is sparingly soluble in water but highly soluble in organic solvents like ethanol and acetone. Chemically, it is reactive, showing electrophilic aromatic substitution and can react with nucleophiles at the substituted positions.

How is 3-Bromo-4-(trifluoromethyl)benzaldehyde (CAS: 372120-55-3) typically synthesized?

3-Bromo-4-(trifluoromethyl)benzaldehyde (CAS: 372120-55-3) is commonly synthesized through electrophilic aromatic substitution reactions, such as the bromination of 4-(trifluoromethyl)benzaldehyde using bromine in the presence of a Lewis acid like aluminum trichloride or iron(III) chloride. The reaction requires a fume hood for safety reasons.

What industries use 3-Bromo-4-(trifluoromethyl)benzaldehyde (CAS: 372120-55-3)?

3-Bromo-4-(trifluoromethyl)benzaldehyde (CAS: 372120-55-3) is primarily used in the pharmaceutical industry for the synthesis of drug intermediates. It can also be utilized in the polymer industry for the preparation of advanced materials and in the sensor industry for developing chemical sensors due to its unique electronic properties.

What precautions should be taken when handling 3-Bromo-4-(trifluoromethyl)benzaldehyde (CAS: 372120-55-3)?

When handling 3-Bromo-4-(trifluoromethyl)benzaldehyde (CAS: 372120-55-3), appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat should be worn. The compound should be stored in a well-ventilated area, preferably in a fume hood, and handled with care to avoid skin contact or inhalation. In case of a spill, consult the Material Safety Data Sheet (MSDS) for appropriate cleanup procedures.