3-Bromo-4-(trifluoromethyl)benzaldehyde(CAS: 372120-55-3)

3-Bromo-4-(trifluoromethyl)benzaldehyde (CAS: 372120-55-3) is a white crystalline solid with a molecular weight of approximately 260.03 g/mol. It is sparingly soluble in water but highly soluble in organic solvents like ethanol and acetone. Chemically, it is reactive, showing electrophilic aromatic substitution and can react with nucleophiles at the substituted positions.

3-Bromo-4-(trifluoromethyl)benzaldehyde (CAS: 372120-55-3) is commonly synthesized through electrophilic aromatic substitution reactions, such as the bromination of 4-(trifluoromethyl)benzaldehyde using bromine in the presence of a Lewis acid like aluminum trichloride or iron(III) chloride. The reaction requires a fume hood for safety reasons.

3-Bromo-4-(trifluoromethyl)benzaldehyde (CAS: 372120-55-3) is primarily used in the pharmaceutical industry for the synthesis of drug intermediates. It can also be utilized in the polymer industry for the preparation of advanced materials and in the sensor industry for developing chemical sensors due to its unique electronic properties.

When handling 3-Bromo-4-(trifluoromethyl)benzaldehyde (CAS: 372120-55-3), appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat should be worn. The compound should be stored in a well-ventilated area, preferably in a fume hood, and handled with care to avoid skin contact or inhalation. In case of a spill, consult the Material Safety Data Sheet (MSDS) for appropriate cleanup procedures.