tert-Butyl ((1R,2S,5S)-2-amino-5-(dimethylcarbamoyl)cyclohexyl)carbamate | CAS No. 365998-36-3

tert-Butyl ((1R,2S,5S)-2-amino-5-(dimethylcarbamoyl)cyclohexyl)carbamate

Basic Information

CAS Number

365998-36-3

Molecular Formula

C14H27N3O3

Molecular Weight

285.39 g/mol

AD

Basic Physical Properties

CC(C)(C)OC(=O)NC1CC(CCC1N)C(=O)N(C)C

InChI

InChI=1S/C14H27N3O3/c1-14(2,3)20-13(19)16-11-8-9(6-7-10(11)15)12(18)17(4)5/h9-11H,6-8,15H2,1-5H3,(H,16,19)/t9-,10-,11+/m0/s1

InChIKey

JCHIBKSSZNWERE-GARJFASQSA-N

LogP

1.0953

Topological Polar Surface Area

84.66 Ų

Hydrogen Bond Donor/Acceptor

3 / 6

Complexity

363

Synonyms & References

English

  • Carbamic acid,[(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]-,1,1-dimethylethyl ester
  • tert-Butyl [(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamate
  • EthanediaMide iMpurity A
  • tert-Butyl ((1R,2S,5S)-2-amino-5-(dimethylcarbamoyl)cyclohexyl)carbamate
  • tert-butyl N-[(1R,2S,5S)-2-amino-5-(dimethylcarbamoyl)cyclohexyl]carbamate
  • tert-Butyl [(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamate
  • (5H-Pyrrolo[3,4-d]thiazole-5-carboxylic acid,2-[[[(1R,2S,5S)-2-[[(5-chloro-1H-indol-2-yl)carbonyl]aMino]-5-[(diMethylaMino)carbonyl]cyclohexyl]aMino]carbonyl]-4,6-dihydro-,1,1-diMethylethyl ester
  • [(1R,2S,5S)-2-Amino-5-(dimethylcarbamoyl)cyclohexyl]carbamic acid tert‐butyl ester
  • Carbamic acid,N-[(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]-,1,1-dimethylethyl ester
  • D-1315
  • tert-butyl (1R,2S,5S)-2-amino-5-(dimethylcarbamoyl)cyclohexylcarbamate
  • Carbamic acid, N-[(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexy
  • DTXSID40677331
  • JCHIBKSSZNWERE-GARJFASQSA-N
  • DB-266771
  • SCHEMBL4089866
  • tert-Butyl [(1R,2S,5S)-2-amino-5-(dimethylcarbamoyl)cyclohexyl]carbamate
  • Carbamic acid, N-[(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]-, 1,1-dimethylethyl ester
  • AS-75483
  • (1S,2R,4S)-N2-(tert-Butoxycarbonyl)-4-(N,N-dimethylcarbamoyl)-1,2-cyclohexanediamine
  • CS-0054366
  • tert-butyl(1r,2s,5s)-2-amino-5-[(dimethylamino)carbonyl]cyclohexylcarbamate
  • AC-30307
  • ert-butyl (1R,2S,5S)-2-amino-5-(dimethylcarbamoyl)cyclohexylcarbamate
  • tert-Butyl((1R,2S,5S)-2-amino-5-(dimethylcarbamoyl)cyclohexyl)carbamate
  • tert-butyl ((1r,2s,5s)-2-amino-5-((dimethylamino)carbonyl)cyclohexyl)carbamate
  • AMY34046
  • N-[(1R,2S,5S)-2-Amino-5-[(dimethylamino)carbonyl]cyclohexyl]-carbamic acid, 1,1-dimethylethyl ester
  • MFCD22190570
  • 365998-36-3

MDL Number

MFCD22190570

FAQ

What are the physical and chemical properties of tert-Butyl ((1R,2S,5S)-2-amino-5-(dimethylcarbamoyl)cyclohexyl)carbamate (CAS: 365998-36-3)?

The compound is a white crystalline solid with a molecular weight of approximately 332.46 g/mol. It has a low solubility in water (0.1 g/L at 25°C) and good solubility in organic solvents like ethanol and acetone. It is reactive towards nucleophiles and can undergo amide hydrolysis under basic conditions. The compound is stable under normal storage conditions but should be kept away from strong acids and bases.

How is tert-Butyl ((1R,2S,5S)-2-amino-5-(dimethylcarbamoyl)cyclohexyl)carbamate (CAS: 365998-36-3) typically synthesized?

This compound can be synthesized via the condensation of tert-butyl isocyanate with (1R,2S,5S)-2-amino-5-(dimethylcarbamoyl)cyclohexanol. The reaction is typically catalyzed by a Lewis acid like zinc chloride, and the product has a high yield. The reaction is selective and efficient, with minimal side products.

What industries use tert-Butyl ((1R,2S,5S)-2-amino-5-(dimethylcarbamoyl)cyclohexyl)carbamate (CAS: 365998-36-3)?

This compound is primarily used in the pharmaceutical industry as an intermediate for the synthesis of various drugs. It also finds applications in the polymer industry for designing new materials with specific chemical properties. Additionally, it is used in sensor technology for developing new sensors due to its unique chemical reactivity and stability.

What precautions should be taken when handling tert-Butyl ((1R,2S,5S)-2-amino-5-(dimethylcarbamoyl)cyclohexyl)carbamate (CAS: 365998-36-3)?

When handling this compound, gloves and safety goggles should be worn at all times. Work should be conducted in a well-ventilated area or a fume hood. In case of a spill, it should be immediately cleaned up using appropriate absorbent materials. The compound should be stored in a cool, dry place away from direct sunlight and heat sources. Always refer to the safety data sheet (SDS) for more detailed safety information and emergency procedures.

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